AlphaFold monomer V2.0 prediction for pre-mRNA-processing factor 6 (O94906)

Structure

1 distinct chain · 63% helix, 1% strand (DSSP).

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Compared structures

• 6QW6 · Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution. · an experimental structure of the same protein · chain A against 5J, TM-score 0.69
• 8QXD · Cryo-EM structure of the cross-exon pre-B complex · an experimental structure of the same protein · chain A against N, TM-score 0.69
• 8R08 · Cryo-EM structure of the cross-exon pre-B+AMPPNP complex · an experimental structure of the same protein · chain A against N, TM-score 0.69
• 8Y6O · Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and… · an experimental structure of the same protein · chain A against G, TM-score 0.68
• 8R0A · Cryo-EM structure of the cross-exon pre-B+5'ss complex · an experimental structure of the same protein · chain A against N, TM-score 0.66
• 8H6J · Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. · an experimental structure of the same protein · chain A against 4G, TM-score 0.64
• 8H6E · Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. · an experimental structure of the same protein · chain A against 4G, TM-score 0.61
• 8QPE · Cryo-EM Structure of Pre-B-like Complex (core part) · an experimental structure of the same protein · chain A against N, TM-score 0.55
• 8QZS · Cryo-EM structure of the cross-exon B-like complex · an experimental structure of the same protein · chain A against N, TM-score 0.55
• 8Q7N · cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region) · an experimental structure of the same protein · chain A against N, TM-score 0.54
• 8QO9 · Cryo-EM structure of a human spliceosomal B complex protomer · an experimental structure of the same protein · chain A against N, TM-score 0.54
• 8R09 · Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex · an experimental structure of the same protein · chain A against N, TM-score 0.54

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt O94906
• Elsewhere: UniProt O94906 · AlphaFold DB O94906