MolNFT v1 · #311208 · protein
AlphaFold monomer V2.0 prediction for U4/U6 small nuclear ribonucleoprotein PRP4 (P20053)
P20053: “AlphaFold monomer V2.0 prediction for U4/U6 small nuclear ribonucleoprotein PRP4 (P20053)”. 3 pockets (best druggability 0.80). MolNFT v1 #311208 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P20053
- Type
- protein
- Length
- 465 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xC0C15E77571eb492a29A53B44C2DeEE0B49693cb
- Molecule
- U4/U6 small nuclear ribonucleoprotein PRP4
- UniProt
- P20053
- Pockets
- 3 · best druggability 0.80
Structure
1 distinct chain · 21% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | U4/U6 small nuclear ribonucleoprotein PRP4 | protein | 465 | 21% helix, 35% strand | P20053 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 905 | 0.80 | 0.83 | 78 | empty |
| 2 | 67 | 0.47 | 0.83 | 17 | empty |
| 3 | 56 | 0.28 | 0.75 | 16 | empty |
Compared structures
- 5NRL · Structure of a pre-catalytic spliceosome · an experimental structure of the same protein · chain A against H, TM-score 0.76
- 5ZWO · Cryo-EM structure of the yeast B complex at average resolution of 3.9 ångström · an experimental structure of the same protein · chain A against K, TM-score 0.76
- 5ZWO · Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom · an experimental structure of the same protein · chain A against K, TM-score 0.76
- 5ZWM · Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom… · an experimental structure of the same protein · chain A against K, TM-score 0.75
- 3JCM · Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snrnp · an experimental structure of the same protein · chain A against B, TM-score 0.75
- 3JCM · Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snRNP · an experimental structure of the same protein · chain A against B, TM-score 0.75
- 5GAP · Body region of the U4/U6.U5 tri-snrnp · an experimental structure of the same protein · chain A against H, TM-score 0.75
- 5GAP · Body region of the U4/U6.U5 tri-snRNP · an experimental structure of the same protein · chain A against H, TM-score 0.75
- 5GAN · The overall structure of the yeast spliceosomal U4/U6.U5 tri-snrnp at 3.7 ångström · an experimental structure of the same protein · chain A against H, TM-score 0.75
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P20053
- Elsewhere: UniProt P20053 · AlphaFold DB P20053
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.