AlphaFold monomer V2.0 prediction for U4/U6 small nuclear ribonucleoprotein PRP4 (P20053)

Structure

1 distinct chain · 21% helix, 35% strand (DSSP).

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Compared structures

• 5NRL · Structure of a pre-catalytic spliceosome · an experimental structure of the same protein · chain A against H, TM-score 0.76
• 5ZWO · Cryo-EM structure of the yeast B complex at average resolution of 3.9 ångström · an experimental structure of the same protein · chain A against K, TM-score 0.76
• 5ZWO · Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom · an experimental structure of the same protein · chain A against K, TM-score 0.76
• 5ZWM · Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom… · an experimental structure of the same protein · chain A against K, TM-score 0.75
• 3JCM · Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snrnp · an experimental structure of the same protein · chain A against B, TM-score 0.75
• 3JCM · Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snRNP · an experimental structure of the same protein · chain A against B, TM-score 0.75
• 5GAP · Body region of the U4/U6.U5 tri-snrnp · an experimental structure of the same protein · chain A against H, TM-score 0.75
• 5GAP · Body region of the U4/U6.U5 tri-snRNP · an experimental structure of the same protein · chain A against H, TM-score 0.75
• 5GAN · The overall structure of the yeast spliceosomal U4/U6.U5 tri-snrnp at 3.7 ångström · an experimental structure of the same protein · chain A against H, TM-score 0.75

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P20053
• Elsewhere: UniProt P20053 · AlphaFold DB P20053