MolNFT v1 · #306429 · protein
AlphaFold monomer V2.0 prediction for alkaline phosphatase (P00634)
P00634: “AlphaFold monomer V2.0 prediction for alkaline phosphatase (P00634)”. 1 pocket (best druggability 0.33). MolNFT v1 #306429 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P00634
- Type
- protein
- Length
- 471 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6a3E2329d7c8AC20c4D0EC099eda7556d5C5b2b5
- Molecule
- Alkaline phosphatase
- UniProt
- P00634
- Pockets
- 1 · best druggability 0.33
Structure
1 distinct chain · 29% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Alkaline phosphatase | protein | 471 | 29% helix, 19% strand | P00634 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 85 | 0.33 | 0.74 | 16 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 1ELX · E. COLI alkaline phosphatase mutant (S102A) · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 1ELX · E. COLI alkaline phosphatase mutant (S102A) · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 1ELZ · E. COLI alkaline phosphatase mutant (S102G) · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 1ELZ · E. COLI alkaline phosphatase mutant (S102G) · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 1ELY · E. COLI alkaline phosphatase mutant (S102C) · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 1ELY · E. COLI alkaline phosphatase mutant (S102C) · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 1B8J · Alkaline phosphatase complexed with vanadate · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 1B8J · Alkaline phosphatase complexed with vanadate · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 1AJB · Three-dimensional structure of the D153G mutant of E. COLI alkaline phosphatase: a mutant… · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 1AJB · Three-dimensional structure of the D153G mutant of E. COLI alkaline phosphatase: a mutant… · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 1ALK · Reaction mechanism of alkaline phosphatase based on crystal structures. two metal ion… · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 1ALK · Reaction mechanism of alkaline phosphatase based on crystal structures. two metal ion… · an experimental structure of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00634
- Elsewhere: UniProt P00634 · AlphaFold DB P00634
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