UniProt P00634
Alkaline phosphatase (P00634)
Alkaline phosphatase (UniProt P00634), EC 3.1.3.1: 119 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 31 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P00634
- Protein
- Alkaline phosphatase
- EC
- 3.1.3.1
- Experimental structures
- 119
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 31 · 5 records with a druggable one
Structures
120 records of P00634 in the MolNFT archive: 119 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AJA | Three-dimensional structure of the D153G mutant of E. COLI alkaline phosphatase: a mutant with… | x-ray diffraction | A, B | — | — |
| 1AJA | Three-dimensional structure of the D153G mutant of E. COLI alkaline phosphatase: a mutant with… | x-ray diffraction | A, B | — | — |
| 1AJB | Three-dimensional structure of the D153G mutant of E. COLI alkaline phosphatase: a mutant with… | x-ray diffraction | A, B | — | — |
| 1AJB | Three-dimensional structure of the D153G mutant of E. COLI alkaline phosphatase: a mutant with… | x-ray diffraction | A, B | — | — |
| 1AJC | Three-dimensional structure of the D153G mutant of E. COLI alkaline phosphatase: a mutant with… | x-ray diffraction | A, B | — | — |
| 1AJC | Three-dimensional structure of the D153G mutant of E. COLI alkaline phosphatase: a mutant with… | x-ray diffraction | A, B | — | — |
| 1AJD | Three-dimensional structure of the D153G mutant of E. COLI alkaline phosphatase: a mutant with… | x-ray diffraction | A, B | — | — |
| 1AJD | Three-dimensional structure of the D153G mutant of E. COLI alkaline phosphatase: a mutant with… | x-ray diffraction | A, B | — | — |
| 1ALH | Kinetics and crystal structure of a mutant E. COLI alkaline phosphatase (asp-369-->asn): a… | x-ray diffraction | A, B | — | — |
| 1ALH | Kinetics and crystal structure of a mutant E. COLI alkaline phosphatase (asp-369-->asn): a… | x-ray diffraction | A, B | — | — |
| 1ALI | Alkaline phosphatase mutant (H412N) | x-ray diffraction | A, B | — | — |
| 1ALI | Alkaline phosphatase mutant (H412N) | x-ray diffraction | A, B | — | — |
| 1ALJ | Alkaline phosphatase mutant (H412N) | x-ray diffraction | A, B | — | — |
| 1ALJ | Alkaline phosphatase mutant (H412N) | x-ray diffraction | A, B | — | — |
| 1ALK | Reaction mechanism of alkaline phosphatase based on crystal structures. two metal ion catalysis | x-ray diffraction | A, B | — | — |
| 1ALK | Reaction mechanism of alkaline phosphatase based on crystal structures. two metal ion catalysis | x-ray diffraction | A, B | — | — |
| 1ANI | Alkaline phosphatase (D153H, K328H) | x-ray diffraction | A, B | — | — |
| 1ANI | Alkaline phosphatase (D153H, K328H) | x-ray diffraction | A, B | — | — |
| 1ANJ | Alkaline phosphatase (K328H) | x-ray diffraction | A, B | — | — |
| 1ANJ | Alkaline phosphatase (K328H) | x-ray diffraction | A, B | — | — |
| 1B8J | Alkaline phosphatase complexed with vanadate | x-ray diffraction | A, B | — | — |
| 1B8J | Alkaline phosphatase complexed with vanadate | x-ray diffraction | A, B | — | — |
| 1ED8 | Structure of E. COLI alkaline phosphatase inhibited by the inorganic phosphate at 1.75A resolution | x-ray diffraction | A, B | — | — |
| 1ED8 | Structure of E. COLI alkaline phosphatase inhibited by the inorganic phosphate at 1.75A resolution | x-ray diffraction | A, B | — | — |
| 1ED9 | Structure of E. COLI alkaline phosphatase without the inorganic phosphate at 1.75A resolution | x-ray diffraction | A, B | — | — |
| 1ED9 | Structure of E. COLI alkaline phosphatase without the inorganic phosphate at 1.75A resolution | x-ray diffraction | A, B | — | — |
| 1ELX | E. COLI alkaline phosphatase mutant (S102A) | x-ray diffraction | A, B | — | — |
| 1ELX | E. COLI alkaline phosphatase mutant (S102A) | x-ray diffraction | A, B | — | — |
| 1ELY | E. COLI alkaline phosphatase mutant (S102C) | x-ray diffraction | A, B | — | — |
| 1ELY | E. COLI alkaline phosphatase mutant (S102C) | x-ray diffraction | A, B | — | — |
| 1ELZ | E. COLI alkaline phosphatase mutant (S102G) | x-ray diffraction | A, B | — | — |
| 1ELZ | E. COLI alkaline phosphatase mutant (S102G) | x-ray diffraction | A, B | — | — |
| 1EW8 | Alkaline phosphatase (E.C. 3.1.3.1) complex with phosphonoacetic acid | x-ray diffraction | A, B | — | — |
| 1EW8 | Alkaline phosphatase (E.C. 3.1.3.1) complex with phosphonoacetic acid | x-ray diffraction | A, B | — | — |
| 1EW9 | Alkaline phosphatase (E.C. 3.1.3.1) complex with mercaptomethyl phosphonate | x-ray diffraction | A, B | — | — |
| 1EW9 | Alkaline phosphatase (E.C. 3.1.3.1) complex with mercaptomethyl phosphonate | x-ray diffraction | A, B | — | — |
| 1HJK | Alkaline phosphatase mutant H331Q | x-ray diffraction | A, B | — | — |
| 1HJK | Alkaline phosphatase mutant H331Q | x-ray diffraction | A, B | — | — |
| 1HQA | Alkaline phosphatase (H412Q) | x-ray diffraction | A, B | — | — |
| 1HQA | Alkaline phosphatase (H412Q) | x-ray diffraction | A, B | — | — |
| 1KH4 | E. COLI alkaline phosphatase mutant (D330N) in complex with phosphate | x-ray diffraction | A, B | — | — |
| 1KH4 | E. COLI alkaline phosphatase mutant (D330N) in complex with phosphate | x-ray diffraction | A, B | — | — |
| 1KH5 | E. COLI alkaline phosphatase mutant (D330N) mimic of the transition states with aluminium fluoride | x-ray diffraction | A, B | — | — |
| 1KH5 | E. COLI alkaline phosphatase mutant (D330N) mimic of the transition states with aluminium fluoride | x-ray diffraction | A, B | — | — |
| 1KH7 | E. COLI alkaline phosphatase mutant (D153GD330N) | x-ray diffraction | A, B | — | — |
| 1KH7 | E. COLI alkaline phosphatase mutant (D153GD330N) | x-ray diffraction | A, B | — | — |
| 1KH9 | E. COLI alkaline phosphatase mutant (D153GD330N) complex with phosphate | x-ray diffraction | A, B | — | — |
| 1KH9 | E. COLI alkaline phosphatase mutant (D153GD330N) complex with phosphate | x-ray diffraction | A, B | — | — |
| 1KHJ | E. COLI alkaline phosphatase mutant (D153HD330N) mimic of the transition states with aluminium… | x-ray diffraction | A, B | — | — |
| 1KHJ | E. COLI alkaline phosphatase mutant (D153HD330N) mimic of the transition states with aluminium… | x-ray diffraction | A, B | — | — |
| 1KHK | E. COLI alkaline phosphatase mutant (D153HD330N) | x-ray diffraction | A, B | — | — |
| 1KHK | E. COLI alkaline phosphatase mutant (D153HD330N) | x-ray diffraction | A, B | — | — |
| 1KHL | E. COLI alkaline phosphatase mutant (D153HD330N) complex with phosphate | x-ray diffraction | A, B | — | — |
| 1KHL | E. COLI alkaline phosphatase mutant (D153HD330N) complex with phosphate | x-ray diffraction | A, B | — | — |
| 1KHN | E. COLI alkaline phosphatase mutant (D153HD330N) zinc form | x-ray diffraction | A, B | — | — |
| 1KHN | E. COLI alkaline phosphatase mutant (D153HD330N) zinc form | x-ray diffraction | A, B | — | — |
| 1URA | Alkaline phosphatase (D51ZN) | x-ray diffraction | A, B | — | — |
| 1URA | Alkaline phosphatase (D51ZN) | x-ray diffraction | A, B | — | — |
| 1URB | Alkaline phosphatase (N51MG) | x-ray diffraction | A, B | — | — |
| 1URB | Alkaline phosphatase (N51MG) | x-ray diffraction | A, B | — | — |
60 records more on the page itself.
Ligands
Experiment against prediction
- 1ELX chain A against the predicted model P00634: TM-score 1.00, RMSD 0.24 Å
- 1ELX chain A against the predicted model P00634: TM-score 1.00, RMSD 0.24 Å
- 3CMR chain A against the predicted model P00634: TM-score 1.00, RMSD 0.26 Å
- 3CMR chain A against the predicted model P00634: TM-score 1.00, RMSD 0.26 Å
- 4KM4 chain A against the predicted model P00634: TM-score 1.00, RMSD 0.28 Å
- 3DYC chain A against the predicted model P00634: TM-score 1.00, RMSD 0.28 Å
- 3DYC chain A against the predicted model P00634: TM-score 1.00, RMSD 0.28 Å
- 2ANH chain A against the predicted model P00634: TM-score 1.00, RMSD 0.34 Å
- 2ANH chain A against the predicted model P00634: TM-score 1.00, RMSD 0.34 Å
- 1HQA chain A against the predicted model P00634: TM-score 1.00, RMSD 0.34 Å
Elsewhere
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