MolNFT v1 · #305906 · protein

AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein phosphatase 2B catalytic subunit (Q4WUR1)

Q4WUR1: “AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein phosphatase 2B catalytic subunit (Q4WUR1)”. 4 pockets (best druggability 0.73). MolNFT v1 #305906 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q4WUR1
Type: protein
Length: 534 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7e2C043327eEBa1c8b012d21202E38bEadf2CE24
Molecule: SERINE/THREONINE-protein phosphatase 2B catalytic subunit
UniProt: Q4WUR1
Pockets: 4 · best druggability 0.73

Structure

1 distinct chain · 45% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SERINE/THREONINE-protein phosphatase 2B catalytic subunit	protein	534	45% helix, 11% strand	Q4WUR1

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	716	0.73	0.79	62	empty
2	163	0.55	0.81	26	empty
3	68	0.32	0.75	12	empty
4	55	0.30	0.76	12	empty

Compared structures

6TZ7 · Crystal structure of aspergillus fumigatus calcineurin a, calcineurin B, FKBP12 and FK506… · an experimental structure of the same protein · chain A against A, TM-score 0.67
7U0U · Crystal structure of a aspergillus fumigatus calcineurin a - calcineurin B fusion bound… · an experimental structure of the same protein · chain A against A, TM-score 0.15

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4WUR1
Elsewhere: UniProt Q4WUR1 · AlphaFold DB Q4WUR1

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