MolNFT v1 · #305051 · protein
AlphaFold monomer V2.0 prediction for DNA polymerase kappa (Q9QUG2)
Q9QUG2: “AlphaFold monomer V2.0 prediction for DNA polymerase kappa (Q9QUG2)”. 7 pockets (best druggability 0.64). MolNFT v1 #305051 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9QUG2
- Type
- protein
- Length
- 852 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x025f3b1a898b05AD2731bE6Ab72687b5920c4A3F
- Molecule
- DNA polymerase kappa
- UniProt
- Q9QUG2
- Pockets
- 7 · best druggability 0.64
Structure
1 distinct chain · 35% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA polymerase kappa | protein | 852 | 35% helix, 11% strand | Q9QUG2 |
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 532 | 0.64 | 0.76 | 60 | empty |
| 2 | 101 | 0.42 | 0.77 | 19 | empty |
| 3 | 115 | 0.40 | 0.75 | 14 | empty |
| 4 | 56 | 0.37 | 0.80 | 15 | empty |
| 5 | 80 | 0.33 | 0.74 | 12 | empty |
Compared structures
- 6C8C · Chimeric pol kappa rir REV1 C-terminal domain in complex with JHRE06 · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 6C8C · Chimeric Pol kappa RIR Rev1 C-terminal domain in complex with JHRE06 · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 6C59 · Chimeric pol kappa rir REV1 C-terminal domain · an experimental structure of the same protein · chain A against A, TM-score 0.06
- 6C59 · Chimeric Pol kappa RIR Rev1 C-terminal domain · an experimental structure of the same protein · chain A against A, TM-score 0.06
- 2LSJ · Solution structure of the mouse Rev1 CTD in complex with the Rev1-interacting Region… · an experimental structure of the same protein · chain A against B, TM-score 0.02
- 2LSJ · Solution structure of the mouse REV1 ctd in complex with the REV1- interacting region… · an experimental structure of the same protein · chain A against B, TM-score 0.02
- 4FJO · Structure of the Rev1 CTD-Rev3/7-Pol kappa RIR complex · an experimental structure of the same protein · chain A against B, TM-score 0.01
- 4FJO · Structure of the REV1 ctd-REV3/7-pol kappa rir complex · an experimental structure of the same protein · chain A against B, TM-score 0.01
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9QUG2
- Elsewhere: UniProt Q9QUG2 · AlphaFold DB Q9QUG2
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