UniProt Q9QUG2
Chimeric protein of the Pol Kappa RIR helix and the Rev1 C-terminal domain (Q9QUG2)
Chimeric protein of the Pol Kappa RIR helix and the Rev1 C-terminal domain (UniProt Q9QUG2), EC 2.7.7.-, 2.7.7.7: 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 8 pockets. Binding sites…
- UniProt
- Q9QUG2
- Protein
- Chimeric protein of the Pol Kappa RIR helix and the Rev1 C-terminal domain
- EC
- 2.7.7.-, 2.7.7.7
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 8 · 2 records with a druggable one
Structures
9 records of Q9QUG2 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LSJ | Solution structure of the mouse Rev1 CTD in complex with the Rev1-interacting Region (RIR)of Pol… | solution nmr | B | — | — |
| 2LSJ | Solution structure of the mouse REV1 ctd in complex with the REV1- interacting region (RIR)OF pol… | solution nmr | B | — | — |
| 4FJO | Structure of the Rev1 CTD-Rev3/7-Pol kappa RIR complex | x-ray diffraction | B | — | — |
| 4FJO | Structure of the REV1 ctd-REV3/7-pol kappa rir complex | x-ray diffraction | B | — | — |
| 6C59 | Chimeric Pol kappa RIR Rev1 C-terminal domain | x-ray diffraction | A | — | — |
| 6C59 | Chimeric pol kappa rir REV1 C-terminal domain | x-ray diffraction | A | — | — |
| 6C8C | Chimeric Pol kappa RIR Rev1 C-terminal domain in complex with JHRE06 | x-ray diffraction | A, B | EQ7 | 1 (best 0.70) |
| 6C8C | Chimeric pol kappa rir REV1 C-terminal domain in complex with JHRE06 | x-ray diffraction | A, B | EQ7 | — |
| Q9QUG2 | AlphaFold monomer V2.0 prediction for DNA polymerase kappa (Q9QUG2) | predicted | A | — | 7 (best 0.64) |
Ligands
- EQ7 · 8-chloro-2-[(2,4-dichlorophenyl)amino]-3-(3-methylbutanoyl)-5-nitroquinolin-4(1H)-one · in 2 records
Experiment against prediction
- 4FJO chain B against the predicted model Q9QUG2: TM-score 0.78, RMSD 0.28 Å
- 4FJO chain B against the predicted model Q9QUG2: TM-score 0.78, RMSD 0.28 Å
- 2LSJ chain B against the predicted model Q9QUG2: TM-score 0.62, RMSD 1.64 Å
- 2LSJ chain B against the predicted model Q9QUG2: TM-score 0.62, RMSD 1.64 Å
- 6C8C chain A against the predicted model Q9QUG2: TM-score 0.36, RMSD 5.02 Å
- 6C8C chain A against the predicted model Q9QUG2: TM-score 0.36, RMSD 5.02 Å
- 6C8C chain B against the predicted model Q9QUG2: TM-score 0.33, RMSD 4.95 Å
- 6C8C chain B against the predicted model Q9QUG2: TM-score 0.33, RMSD 4.95 Å
- 6C59 chain A against the predicted model Q9QUG2: TM-score 0.32, RMSD 4.81 Å
- 6C59 chain A against the predicted model Q9QUG2: TM-score 0.32, RMSD 4.81 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.