MolNFT v1 · #303351 · protein
AlphaFold monomer V2.0 prediction for protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (Q5NDF2)
Q5NDF2: “AlphaFold monomer V2.0 prediction for protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2…”. 4 pockets (best druggability 0.70). MolNFT v1 #303351 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q5NDF2
- Type
- protein
- Length
- 580 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1ED4a68B4011314730adE976b56Ad4cA21b54dcD
- Molecule
- Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2
- UniProt
- Q5NDF2
- Pockets
- 4 · best druggability 0.70
Structure
1 distinct chain · 33% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 | protein | 580 | 33% helix, 25% strand | Q5NDF2 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 468 | 0.70 | 0.80 | 50 | empty |
| 2 | 149 | 0.50 | 0.79 | 31 | empty |
| 3 | 159 | 0.43 | 0.75 | 27 | empty |
| 4 | 66 | 0.33 | 0.76 | 14 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 7E9L · Crystal Structure of POMGNT2 in complex with UDP and mono-mannosyl peptide (379Man short… · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 7E9L · Crystal structure of POMGNT2 in complex with udp and mono-mannosyl peptide (379MAN short… · an experimental structure of the same protein · chain A against A, TM-score 0.85
- 7E9K · Crystal structure of POMGNT2 in complex with udp and mono-mannosyl peptide (379MAN long… · an experimental structure of the same protein · chain A against B, TM-score 0.84
- 7E9K · Crystal Structure of POMGNT2 in complex with UDP and mono-mannosyl peptide (379Man long… · an experimental structure of the same protein · chain A against B, TM-score 0.84
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5NDF2
- Elsewhere: UniProt Q5NDF2 · AlphaFold DB Q5NDF2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.