AlphaFold monomer V2.0 prediction for plexin-A1 (P70206)

Structure

1 distinct chain · 26% helix, 30% strand (DSSP).

Pockets

15 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 24 disulfide (disulfide).

Compared structures

• 5L56 · Plexin A1 full extracellular region, domains 1 to 10, to 4 ångström · an experimental structure of the same protein · chain A against A, TM-score 0.61
• 5L56 · Plexin A1 full extracellular region, domains 1 to 10, to 4 angstrom · an experimental structure of the same protein · chain A against A, TM-score 0.61
• 5L59 · Plexin A1 full extracellular region, domains 1 to 10, to 6 ångström, spacegroup P2(1) · an experimental structure of the same protein · chain A against A, TM-score 0.55
• 5L5C · Plexin A1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup P4(3)2(1)2 · an experimental structure of the same protein · chain A against A, TM-score 0.50
• 5L5C · Plexin A1 full extracellular region, domains 1 to 10, to 6 ångström, spacegroup P4(3)2(1)2 · an experimental structure of the same protein · chain A against A, TM-score 0.50
• 3RYT · The Plexin A1 intracellular region in complex with Rac1 · an experimental structure of the same protein · chain A against A, TM-score 0.27
• 3RYT · The plexin A1 intracellular region in complex with RAC1 · an experimental structure of the same protein · chain A against A, TM-score 0.27
• 5L7N · Plexin A1 extracellular fragment, domains 7-10 (IPT3-IPT6) · an experimental structure of the same protein · chain A against A, TM-score 0.18

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P70206
• Elsewhere: UniProt P70206 · AlphaFold DB P70206