UniProt P70206
Plexin-A1 (P70206)
Plexin-A1 (UniProt P70206): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 25 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P70206
- Protein
- Plexin-A1
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 25 · 2 records with a druggable one
Structures
9 records of P70206 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3RYT | The Plexin A1 intracellular region in complex with Rac1 | x-ray diffraction | A, B | — | — |
| 3RYT | The plexin A1 intracellular region in complex with RAC1 | x-ray diffraction | A, B | — | — |
| 5L56 | Plexin A1 full extracellular region, domains 1 to 10, to 4 angstrom | x-ray diffraction | A | NAG, MAN | — |
| 5L56 | Plexin A1 full extracellular region, domains 1 to 10, to 4 ångström | x-ray diffraction | A | NAG, MAN | — |
| 5L59 | Plexin A1 full extracellular region, domains 1 to 10, to 6 ångström, spacegroup P2(1) | x-ray diffraction | A, B | NAG, MAN | — |
| 5L5C | Plexin A1 full extracellular region, domains 1 to 10, to 6 angstrom, spacegroup P4(3)2(1)2 | x-ray diffraction | A | NAG, MAN | 10 (best 0.76) |
| 5L5C | Plexin A1 full extracellular region, domains 1 to 10, to 6 ångström, spacegroup P4(3)2(1)2 | x-ray diffraction | A | NAG, MAN | — |
| 5L7N | Plexin A1 extracellular fragment, domains 7-10 (IPT3-IPT6) | x-ray diffraction | A | NAG | — |
| P70206 | AlphaFold monomer V2.0 prediction for plexin-A1 (P70206) | predicted | A | — | 15 (best 0.79) |
Ligands
Experiment against prediction
- 5L7N chain A against the predicted model P70206: TM-score 0.99, RMSD 0.81 Å
- 5L56 chain A against the predicted model P70206: TM-score 0.97, RMSD 1.82 Å
- 5L56 chain A against the predicted model P70206: TM-score 0.97, RMSD 1.82 Å
- 3RYT chain A against the predicted model P70206: TM-score 0.95, RMSD 1.72 Å
- 3RYT chain A against the predicted model P70206: TM-score 0.95, RMSD 1.72 Å
- 3RYT chain B against the predicted model P70206: TM-score 0.94, RMSD 1.86 Å
- 3RYT chain B against the predicted model P70206: TM-score 0.94, RMSD 1.86 Å
- 5L59 chain A against the predicted model P70206: TM-score 0.87, RMSD 4.91 Å
- 5L5C chain A against the predicted model P70206: TM-score 0.77, RMSD 6.51 Å
- 5L5C chain A against the predicted model P70206: TM-score 0.77, RMSD 6.51 Å
Elsewhere
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