GL1X · GenesisL1 explorer

MolNFT v1 · #300863 · protein

AlphaFold monomer V2.0 prediction for phospholipase a-2-activating protein (Q9Y263)

Q9Y263: “AlphaFold monomer V2.0 prediction for phospholipase a-2-activating protein (Q9Y263)”. 7 pockets (best druggability 0.78). MolNFT v1 #300863 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9Y263
Type
protein
Length
795 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xB0755A2f7771BeB09D59dEE34388c0C970c91251
Molecule
Phospholipase a-2-activating protein
UniProt
Q9Y263
Pockets
7 · best druggability 0.78

Structure

1 distinct chain · 30% helix, 27% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APhospholipase a-2-activating proteinprotein79530% helix, 27% strandQ9Y263

Pockets

7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
19950.780.8093empty
25890.750.8258empty
31420.740.9322empty
41540.530.8020empty
5690.410.8019empty

Compared structures

  • 3EBB · PLAP/P97 complex · an experimental structure of the same protein · chain A against A, TM-score 0.33
  • 3EBB · PLAP/P97 complex · an experimental structure of the same protein · chain A against A, TM-score 0.33
  • 2K89 · Solution structure of a novel Ubiquitin-binding domain from Human PLAA (PFUC, Gly76-Pro77… · an experimental structure of the same protein · chain A against A, TM-score 0.08
  • 2K89 · Solution structure of a novel ubiquitin-binding domain from human plaa (pfuc, GLY76-PRO77… · an experimental structure of the same protein · chain A against A, TM-score 0.08
  • 2K8B · Solution structure of PLAA family ubiquitin binding domain (PFUC) cis isomer in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.08
  • 2K8B · Solution structure of plaa family ubiquitin binding domain (pfuc) cis isomer in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.08

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