MolNFT v1 · #300764 · protein

AlphaFold monomer V2.0 prediction for polyketide biosynthesis acyltransferase homolog pksd (O34877)

O34877: “AlphaFold monomer V2.0 prediction for polyketide biosynthesis acyltransferase homolog pksd (O34877)”. 2 pockets (best druggability 0.65). MolNFT v1 #300764 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: O34877
Type: protein
Length: 324 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x57764D56d6101A81058fB5c5E4A885853213A02B
Molecule: Polyketide biosynthesis acyltransferase homolog pksd
UniProt: O34877
Pockets: 2 · best druggability 0.65

Structure

1 distinct chain · 48% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Polyketide biosynthesis acyltransferase homolog pksd	protein	324	48% helix, 14% strand	O34877

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	201	0.65	0.84	36	empty
2	67	0.33	0.76	14	empty

Compared structures

8AW0 · Crystal structure of PksD, the trans-acting acyl hydrolase domain from the bacillaene… · an experimental structure of the same protein · chain A against A, TM-score 0.97
8AVZ · Crystal structure of PksD, the trans-acting acyl hydrolase domain from the bacillaene… · an experimental structure of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O34877
Elsewhere: UniProt O34877 · AlphaFold DB O34877

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