GL1X · GenesisL1 explorer

MolNFT v1 · #298534 · protein

AlphaFold monomer V2.0 prediction for virulence sensor histidine kinase phoq (P0DM80)

P0DM80: “AlphaFold monomer V2.0 prediction for virulence sensor histidine kinase phoq (P0DM80)”. 4 pockets (best druggability 0.67). MolNFT v1 #298534 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P0DM80
Type
protein
Length
487 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x35612D34a32C306CA4fc1edA9360D1F717e25950
Molecule
Virulence sensor histidine kinase phoq
UniProt
P0DM80
Pockets
4 · best druggability 0.67

Structure

1 distinct chain · 53% helix, 18% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AVirulence sensor histidine kinase phoqprotein48753% helix, 18% strandP0DM80

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13510.670.8148empty
22140.510.7619empty
3550.330.7813empty
4610.310.7513empty

Compared structures

  • 4UEY · Structure of the periplasmic domain phoq double mutant (W104C-A128C) · an experimental structure of the same protein · chain A against A, TM-score 0.28
  • 4UEY · Structure of the periplasmic domain PhoQ double mutant (W104C-A128C) · an experimental structure of the same protein · chain A against A, TM-score 0.28

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