MolNFT v1 · #297123 · protein
AlphaFold monomer V2.0 prediction for bifunctional PHOSPHOGLUCOSE/PHOSPHOMANNOSE isomerase (Q8ZWV0)
Q8ZWV0: “AlphaFold monomer V2.0 prediction for bifunctional PHOSPHOGLUCOSE/PHOSPHOMANNOSE isomerase (Q8ZWV0)”. 2 pockets (best druggability 0.54). MolNFT v1 #297123 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8ZWV0
- Type
- protein
- Length
- 302 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xC5423C95BD2c5b7EB8e3A2f399D357489A01C1e7
- Molecule
- Bifunctional PHOSPHOGLUCOSE/PHOSPHOMANNOSE isomerase
- UniProt
- Q8ZWV0
- Pockets
- 2 · best druggability 0.54
Structure
1 distinct chain · 46% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Bifunctional PHOSPHOGLUCOSE/PHOSPHOMANNOSE isomerase | protein | 302 | 46% helix, 17% strand | Q8ZWV0 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 300 | 0.54 | 0.75 | 34 | empty |
| 2 | 58 | 0.30 | 0.75 | 14 | empty |
Compared structures
- 1TZB · Crystal structure of native phosphoglucose/phosphomannose isomerase from Pyrobaculum… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1TZB · Crystal structure of native PHOSPHOGLUCOSE/PHOSPHOMANNOSE isomerase from pyrobaculum… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1TZC · Crystal structure of phosphoglucose/phosphomannose isomerase from Pyrobaculum aerophilum… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1TZC · Crystal structure of PHOSPHOGLUCOSE/PHOSPHOMANNOSE isomerase from pyrobaculum aerophilum… · an experimental structure of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8ZWV0
- Elsewhere: UniProt Q8ZWV0 · AlphaFold DB Q8ZWV0
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