MolNFT v1 · #295098 · protein
AlphaFold monomer V2.0 prediction for peroxisomal targeting signal 1 receptor (P50542)
P50542: “AlphaFold monomer V2.0 prediction for peroxisomal targeting signal 1 receptor (P50542)”. 4 pockets (best druggability 0.70). MolNFT v1 #295098 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P50542
- Type
- protein
- Length
- 639 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xb3c0C983Fc44934AC589D7131C08a72544EBB92E
- Molecule
- Peroxisomal targeting signal 1 receptor
- UniProt
- P50542
- Pockets
- 4 · best druggability 0.70
Structure
1 distinct chain · 60% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Peroxisomal targeting signal 1 receptor | protein | 639 | 60% helix, 0% strand | P50542 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 496 | 0.70 | 0.80 | 55 | empty |
| 2 | 201 | 0.62 | 0.83 | 40 | empty |
| 3 | 108 | 0.46 | 0.79 | 17 | empty |
| 4 | 54 | 0.27 | 0.74 | 14 | empty |
Compared structures
- 1FCH · Crystal structure of the PTS1 complexed to the tpr region of human PEX5 · an experimental structure of the same protein · chain A against A, TM-score 0.46
- 1FCH · Crystal structure of the PTS1 complexed to the tpr region of human PEX5 · an experimental structure of the same protein · chain A against A, TM-score 0.46
- 3R9A · Human alanine-glyoxylate aminotransferase in complex with the tpr domain of human PEX5P · an experimental structure of the same protein · chain A against D, TM-score 0.45
- 3R9A · Human alanine-glyoxylate aminotransferase in complex with the TPR domain of human PEX5P · an experimental structure of the same protein · chain A against D, TM-score 0.45
- 4KXK · Alanine-glyoxylate aminotransferase variant K390A/K391A in complex with the TPR domain of… · an experimental structure of the same protein · chain A against B, TM-score 0.45
- 4KXK · Alanine-glyoxylate aminotransferase variant K390A/K391A in complex with the tpr domain of… · an experimental structure of the same protein · chain A against B, TM-score 0.45
- 4KYO · Alanine-glyoxylate aminotransferase variant K390A in complex with the tpr domain of human… · an experimental structure of the same protein · chain A against B, TM-score 0.45
- 4KYO · Alanine-glyoxylate aminotransferase variant K390A in complex with the TPR domain of human… · an experimental structure of the same protein · chain A against B, TM-score 0.45
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P50542
- Elsewhere: UniProt P50542 · AlphaFold DB P50542
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