UniProt P50542
Peroxisomal targeting signal 1 receptor (P50542)
Peroxisomal targeting signal 1 receptor (UniProt P50542): 19 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P50542
- Protein
- Peroxisomal targeting signal 1 receptor
- Experimental structures
- 19
- Predicted models
- 1
- Pockets
- 6 · 2 records with a druggable one
Structures
20 records of P50542 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1FCH | Crystal structure of the PTS1 complexed to the tpr region of human PEX5 | x-ray diffraction | A, B | — | — |
| 1FCH | Crystal structure of the PTS1 complexed to the tpr region of human PEX5 | x-ray diffraction | A, B | — | — |
| 2C0L | Tpr domain of human PEX5P in complex with human MSCP2 | x-ray diffraction | A | — | — |
| 2C0L | Tpr domain of human PEX5P in complex with human MSCP2 | x-ray diffraction | A | — | — |
| 2C0M | apo form of the TPR domain of the pex5p receptor | x-ray diffraction | A, B, C, F | — | — |
| 2C0M | Apo form of the tpr domain of the PEX5P receptor | x-ray diffraction | A, B, C, F | — | — |
| 2J9Q | A novel conformation for the TPR domain of pex5p | x-ray diffraction | A, B | — | — |
| 2J9Q | A novel conformation for the tpr domain of PEX5P | x-ray diffraction | A, B | — | — |
| 2W84 | Structure of Pex14 in complex with Pex5 | solution nmr | B | — | — |
| 2W84 | Structure of PEX14 in complex with PEX5 | solution nmr | B | — | — |
| 3R9A | Human alanine-glyoxylate aminotransferase in complex with the TPR domain of human PEX5P | x-ray diffraction | B, D | — | — |
| 3R9A | Human alanine-glyoxylate aminotransferase in complex with the tpr domain of human PEX5P | x-ray diffraction | B, D | — | — |
| 4BXU | Structure of Pex14 in complex with Pex5 LVxEF motif | solution nmr | B | — | — |
| 4BXU | Structure of PEX14 in complex with PEX5 lvxef motif | solution nmr | B | — | — |
| 4KXK | Alanine-glyoxylate aminotransferase variant K390A/K391A in complex with the TPR domain of human… | x-ray diffraction | B, D | — | — |
| 4KXK | Alanine-glyoxylate aminotransferase variant K390A/K391A in complex with the tpr domain of human… | x-ray diffraction | B, D | — | — |
| 4KYO | Alanine-glyoxylate aminotransferase variant K390A in complex with the TPR domain of human Pex5p | x-ray diffraction | B, D | — | — |
| 4KYO | Alanine-glyoxylate aminotransferase variant K390A in complex with the tpr domain of human PEX5P | x-ray diffraction | B, D | — | — |
| 9GAG | Human PEX5 TPR domain in complex with PEX14 KIPSWQIPV peptide | solution nmr | A | — | 2 (best 0.63) |
| P50542 | AlphaFold monomer V2.0 prediction for peroxisomal targeting signal 1 receptor (P50542) | predicted | A | — | 4 (best 0.70) |
Experiment against prediction
- 4KYO chain D against the predicted model P50542: TM-score 0.99, RMSD 0.64 Å
- 4KYO chain D against the predicted model P50542: TM-score 0.99, RMSD 0.64 Å
- 4KYO chain B against the predicted model P50542: TM-score 0.99, RMSD 0.66 Å
- 4KYO chain B against the predicted model P50542: TM-score 0.99, RMSD 0.66 Å
- 4KXK chain B against the predicted model P50542: TM-score 0.99, RMSD 0.76 Å
- 4KXK chain B against the predicted model P50542: TM-score 0.99, RMSD 0.76 Å
- 3R9A chain B against the predicted model P50542: TM-score 0.98, RMSD 0.93 Å
- 3R9A chain B against the predicted model P50542: TM-score 0.98, RMSD 0.93 Å
- 3R9A chain D against the predicted model P50542: TM-score 0.97, RMSD 1.10 Å
- 3R9A chain D against the predicted model P50542: TM-score 0.97, RMSD 1.10 Å
Elsewhere
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