MolNFT v1 · #295021 · protein
AlphaFold monomer V2.0 prediction for peroxisomal biogenesis factor 19 (P40855)
P40855: “AlphaFold monomer V2.0 prediction for peroxisomal biogenesis factor 19 (P40855)”. 2 pockets (best druggability 0.49). MolNFT v1 #295021 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P40855
- Type
- protein
- Length
- 299 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9B130d619fCFc21d0D08E5Ce38Cf42A5fbe230CB
- Molecule
- Peroxisomal biogenesis factor 19
- UniProt
- P40855
- Pockets
- 2 · best druggability 0.49
Structure
1 distinct chain · 65% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Peroxisomal biogenesis factor 19 | protein | 299 | 65% helix, 0% strand | P40855 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 131 | 0.49 | 0.78 | 14 | empty |
| 2 | 90 | 0.38 | 0.76 | 12 | empty |
Compared structures
- 2WL8 · X-ray crystal structure of PEX19P · an experimental structure of the same protein · chain A against A, TM-score 0.36
- 2WL8 · X-ray crystal structure of Pex19p · an experimental structure of the same protein · chain A against A, TM-score 0.36
- 5LNF · Solution NMR structure of farnesylated PEX19, C-terminal domain · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 5LNF · Solution NMR structure of farnesylated PEX19, C-terminal domain · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 3AJB · Crystal structure of human PEX3P in complex with N-terminal PEX19P peptide · an experimental structure of the same protein · chain A against B, TM-score 0.07
- 3AJB · Crystal Structure of human Pex3p in complex with N-terminal Pex19p peptide · an experimental structure of the same protein · chain A against B, TM-score 0.07
- 3MK4 · X-Ray structure of human PEX3 in complex with a PEX19 derived peptide · an experimental structure of the same protein · chain A against B, TM-score 0.05
- 3MK4 · X-ray structure of human PEX3 in complex with a PEX19 derived peptide · an experimental structure of the same protein · chain A against B, TM-score 0.05
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P40855
- Elsewhere: UniProt P40855 · AlphaFold DB P40855
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