MolNFT v1 · #292933 · protein
AlphaFold monomer V2.0 prediction for inactive tyrosine-protein kinase PEAK1 (Q9H792)
Q9H792: “AlphaFold monomer V2.0 prediction for inactive tyrosine-protein kinase PEAK1 (Q9H792)”. 10 pockets (best druggability 0.64). MolNFT v1 #292933 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9H792
- Type
- protein
- Length
- 1,746 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xF8cD1d8d93E9783063700De244A6e3cf6A195579
- Molecule
- Inactive tyrosine-protein kinase PEAK1
- UniProt
- Q9H792
- Pockets
- 10 · best druggability 0.64
Structure
1 distinct chain · 16% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Inactive tyrosine-protein kinase PEAK1 | protein | 1746 | 16% helix, 4% strand | Q9H792 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 498 | 0.64 | 0.77 | 45 | empty |
| 2 | 327 | 0.60 | 0.77 | 35 | empty |
| 3 | 184 | 0.57 | 0.81 | 21 | empty |
| 4 | 279 | 0.56 | 0.77 | 23 | empty |
| 5 | 253 | 0.50 | 0.74 | 28 | empty |
Compared structures
- 6BHC · Crystal structure of pseduokinase PEAK1 (sugen kinase 269) · an experimental structure of the same protein · chain A against A, TM-score 0.21
- 6BHC · Crystal structure of pseduokinase PEAK1 (Sugen Kinase 269) · an experimental structure of the same protein · chain A against A, TM-score 0.21
- 8DGM · 14-3-3 epsilon bound to phosphorylated PEAK1 (pT1165) peptide · an experimental structure of the same protein · chain A against B, TM-score 0.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H792
- Elsewhere: UniProt Q9H792 · AlphaFold DB Q9H792
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