MolNFT v1 · #289224 · protein
AlphaFold monomer V2.0 prediction for POLY(RC)-binding protein 2 (Q15366)
Q15366: “AlphaFold monomer V2.0 prediction for POLY(RC)-binding protein 2 (Q15366)”. 4 pockets (best druggability 0.43). MolNFT v1 #289224 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q15366
- Type
- protein
- Length
- 365 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x2c85861fb629Fbee3DC9f74281A6C51a1178d8d4
- Molecule
- POLY(RC)-binding protein 2
- UniProt
- Q15366
- Pockets
- 4 · best druggability 0.43
Structure
1 distinct chain · 33% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | POLY(RC)-binding protein 2 | protein | 365 | 33% helix, 17% strand | Q15366 |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 90 | 0.43 | 0.78 | 18 | empty |
| 2 | 80 | 0.41 | 0.78 | 19 | empty |
| 3 | 107 | 0.36 | 0.74 | 18 | empty |
| 4 | 55 | 0.35 | 0.78 | 16 | empty |
Compared structures
- 2JZX · PCBP2 KH1-KH2 domains · an experimental structure of the same protein · chain A against A, TM-score 0.40
- 2JZX · PCBP2 KH1-KH2 domains · an experimental structure of the same protein · chain A against A, TM-score 0.40
- 2P2R · Crystal structure of the third kh domain of human POLY(C)-binding protein-2 in complex… · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 2P2R · Crystal structure of the third KH domain of human Poly(C)-Binding Protein-2 in complex… · an experimental structure of the same protein · chain A against A, TM-score 0.20
- 2AXY · Crystal Structure of KH1 domain of human Poly(C)-binding protein-2 with C-rich strand of… · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 2AXY · Crystal structure of KH1 domain of human POLY(C)-binding protein-2 with C-rich strand of… · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 2PY9 · Protein-RNA Interaction involving KH1 domain from Human Poly(C)-Binding Protein-2 · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 2PY9 · Protein-RNA interaction involving KH1 domain from human POLY(C)-binding protein-2 · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 2PQU · Crystal structure of KH1 domain of human PCBP2 complexed to single-stranded 12-mer… · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 2PQU · Crystal structure of KH1 domain of human PCBP2 complexed to single- stranded 12-mer… · an experimental structure of the same protein · chain A against A, TM-score 0.19
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15366
- Elsewhere: UniProt Q15366 · AlphaFold DB Q15366
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