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AlphaFold monomer V2.0 prediction for POLY(RC)-binding protein 2 (Q15366)

Analyse AlphaFold monomer V2.0 prediction for POLY(RC)-binding protein 2 (Q15366) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q15366
Type
protein
Length
365 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x2c85861fb629Fbee3DC9f74281A6C51a1178d8d4
Molecule
POLY(RC)-binding protein 2
UniProt
Q15366
Pockets
4 · best druggability 0.43

Structure

1 distinct chain · 33% helix, 17% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APOLY(RC)-binding protein 2protein36533% helix, 17% strandQ15366

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1900.430.7818empty
2800.410.7819empty
31070.360.7418empty
4550.350.7816empty

Compared structures

  • 2JZX · PCBP2 KH1-KH2 domains · an experimental structure of the same protein · chain A against A, TM-score 0.40
  • 2JZX · PCBP2 KH1-KH2 domains · an experimental structure of the same protein · chain A against A, TM-score 0.40
  • 2P2R · Crystal structure of the third kh domain of human POLY(C)-binding protein-2 in complex… · an experimental structure of the same protein · chain A against A, TM-score 0.20
  • 2P2R · Crystal structure of the third KH domain of human Poly(C)-Binding Protein-2 in complex… · an experimental structure of the same protein · chain A against A, TM-score 0.20
  • 2AXY · Crystal Structure of KH1 domain of human Poly(C)-binding protein-2 with C-rich strand of… · an experimental structure of the same protein · chain A against A, TM-score 0.19
  • 2AXY · Crystal structure of KH1 domain of human POLY(C)-binding protein-2 with C-rich strand of… · an experimental structure of the same protein · chain A against A, TM-score 0.19
  • 2PY9 · Protein-RNA Interaction involving KH1 domain from Human Poly(C)-Binding Protein-2 · an experimental structure of the same protein · chain A against A, TM-score 0.19
  • 2PY9 · Protein-RNA interaction involving KH1 domain from human POLY(C)-binding protein-2 · an experimental structure of the same protein · chain A against A, TM-score 0.19
  • 2PQU · Crystal structure of KH1 domain of human PCBP2 complexed to single-stranded 12-mer… · an experimental structure of the same protein · chain A against A, TM-score 0.19
  • 2PQU · Crystal structure of KH1 domain of human PCBP2 complexed to single- stranded 12-mer… · an experimental structure of the same protein · chain A against A, TM-score 0.19

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