MolNFT v1 · #289107 · protein
AlphaFold monomer V2.0 prediction for penicillin-binding protein 2X (P14677)
P14677: “AlphaFold monomer V2.0 prediction for penicillin-binding protein 2X (P14677)”. 8 pockets (best druggability 0.73). MolNFT v1 #289107 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P14677
- Type
- protein
- Length
- 750 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6dF8740DB66EA0E28dc7A9ed64F13eCBcdEEd7D9
- Molecule
- Penicillin-binding protein 2X
- UniProt
- P14677
- Pockets
- 8 · best druggability 0.73
Structure
1 distinct chain · 33% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Penicillin-binding protein 2X | protein | 750 | 33% helix, 25% strand | P14677 |
Pockets
8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 340 | 0.73 | 0.85 | 42 | empty |
| 2 | 400 | 0.64 | 0.78 | 47 | empty |
| 3 | 119 | 0.37 | 0.74 | 21 | empty |
| 4 | 107 | 0.37 | 0.74 | 16 | empty |
| 5 | 63 | 0.34 | 0.77 | 16 | empty |
Compared structures
- 1RP5 · PBP2x from Streptococcus pneumoniae strain 5259 with reduced susceptibility to… · an experimental structure of the same protein · chain A against A, TM-score 0.80
- 1RP5 · PBP2X from streptococcus pneumoniae strain 5259 with reduced susceptibility to… · an experimental structure of the same protein · chain A against A, TM-score 0.80
- 1PMD · Penicillin-binding protein 2X (pbp-2X) · an experimental structure of the same protein · chain A against A, TM-score 0.77
- 1PMD · Penicillin-binding protein 2X (pbp-2X) · an experimental structure of the same protein · chain A against A, TM-score 0.77
- 1QME · Penicillin-binding protein 2X (pbp-2X) · an experimental structure of the same protein · chain A against A, TM-score 0.74
- 1QME · Penicillin-binding protein 2X (pbp-2X) · an experimental structure of the same protein · chain A against A, TM-score 0.74
- 1QMF · Penicillin-binding protein 2X (pbp-2X) acyl-enzyme complex · an experimental structure of the same protein · chain A against A, TM-score 0.74
- 1QMF · Penicillin-binding protein 2X (pbp-2X) acyl-enzyme complex · an experimental structure of the same protein · chain A against A, TM-score 0.74
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14677
- Elsewhere: UniProt P14677 · AlphaFold DB P14677
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