UniProt P14677
Penicillin-binding protein 2X (P14677)
Penicillin-binding protein 2X (UniProt P14677): 8 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P14677
- Protein
- Penicillin-binding protein 2X
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
9 records of P14677 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PMD | Penicillin-binding protein 2X (pbp-2X) | x-ray diffraction | A | — | — |
| 1PMD | Penicillin-binding protein 2X (pbp-2X) | x-ray diffraction | A | — | — |
| 1QME | Penicillin-binding protein 2X (pbp-2X) | x-ray diffraction | A | — | — |
| 1QME | Penicillin-binding protein 2X (pbp-2X) | x-ray diffraction | A | — | — |
| 1QMF | Penicillin-binding protein 2X (pbp-2X) acyl-enzyme complex | x-ray diffraction | A | — | — |
| 1QMF | Penicillin-binding protein 2X (pbp-2X) acyl-enzyme complex | x-ray diffraction | A | — | — |
| 1RP5 | PBP2x from Streptococcus pneumoniae strain 5259 with reduced susceptibility to beta-lactam… | x-ray diffraction | A, B | — | — |
| 1RP5 | PBP2X from streptococcus pneumoniae strain 5259 with reduced susceptibility to beta-lactam… | x-ray diffraction | A, B | — | — |
| P14677 | AlphaFold monomer V2.0 prediction for penicillin-binding protein 2X (P14677) | predicted | A | — | 8 (best 0.73) |
Experiment against prediction
- 1QME chain A against the predicted model P14677: TM-score 0.99, RMSD 0.73 Å
- 1QME chain A against the predicted model P14677: TM-score 0.99, RMSD 0.73 Å
- 1QMF chain A against the predicted model P14677: TM-score 0.99, RMSD 0.96 Å
- 1QMF chain A against the predicted model P14677: TM-score 0.99, RMSD 0.96 Å
- 1RP5 chain A against the predicted model P14677: TM-score 0.88, RMSD 2.92 Å
- 1RP5 chain A against the predicted model P14677: TM-score 0.88, RMSD 2.92 Å
- 1RP5 chain B against the predicted model P14677: TM-score 0.87, RMSD 2.34 Å
- 1RP5 chain B against the predicted model P14677: TM-score 0.87, RMSD 2.34 Å
- 1PMD chain A against the predicted model P14677: TM-score 0.85, RMSD 3.54 Å
- 1PMD chain A against the predicted model P14677: TM-score 0.85, RMSD 3.54 Å
Elsewhere
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