MolNFT v1 · #289056 · protein
AlphaFold monomer V2.0 prediction for penicillin-binding protein 1A (O66874)
O66874: “AlphaFold monomer V2.0 prediction for penicillin-binding protein 1A (O66874)”. 7 pockets (best druggability 0.58). MolNFT v1 #289056 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O66874
- Type
- protein
- Length
- 726 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x429aA010A80A47FF4a2777bB34A2bba144d19df2
- Molecule
- Penicillin-binding protein 1A
- UniProt
- O66874
- Pockets
- 7 · best druggability 0.58
Structure
1 distinct chain · 42% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Penicillin-binding protein 1A | protein | 726 | 42% helix, 19% strand | O66874 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 250 | 0.58 | 0.79 | 36 | empty |
| 2 | 163 | 0.54 | 0.80 | 25 | empty |
| 3 | 216 | 0.53 | 0.78 | 26 | empty |
| 4 | 201 | 0.49 | 0.75 | 27 | empty |
| 5 | 80 | 0.41 | 0.79 | 16 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 3NB6 · Crystal structure of aquifex aeolicus peptidoglycan glycosyltransferase in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 3NB6 · Crystal structure of Aquifex aeolicus peptidoglycan glycosyltransferase in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 2OQO · Crystal structure of a peptidoglycan glycosyltransferase from a class a pbp: insight into… · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 2OQO · Crystal structure of a peptidoglycan glycosyltransferase from a class A PBP: insight into… · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 3NB7 · Crystal structure of aquifex aeolicus peptidoglycan glycosyltransferase in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.24
- 3NB7 · Crystal structure of Aquifex Aeolicus Peptidoglycan Glycosyltransferase in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.24
- 3D3H · Crystal structure of a complex of the peptidoglycan glycosyltransferase domain from… · an experimental structure of the same protein · chain A against A, TM-score 0.24
- 3D3H · Crystal structure of a complex of the peptidoglycan glycosyltransferase domain from… · an experimental structure of the same protein · chain A against A, TM-score 0.24
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O66874
- Elsewhere: UniProt O66874 · AlphaFold DB O66874
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.