MolNFT v1 · #283004 · protein
AlphaFold monomer V2.0 prediction for oxysterol-binding protein 1 (P22059)
P22059: “AlphaFold monomer V2.0 prediction for oxysterol-binding protein 1 (P22059)”. 8 pockets (best druggability 0.82). MolNFT v1 #283004 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P22059
- Type
- protein
- Length
- 807 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x356A98300827Dd8A16B914ED13C2114FD83b1072
- Molecule
- Oxysterol-binding protein 1
- UniProt
- P22059
- Pockets
- 8 · best druggability 0.82
Structure
1 distinct chain · 32% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Oxysterol-binding protein 1 | protein | 807 | 32% helix, 21% strand | P22059 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 684 | 0.82 | 0.86 | 67 | empty |
| 2 | 320 | 0.56 | 0.75 | 30 | empty |
| 3 | 154 | 0.55 | 0.81 | 24 | empty |
| 4 | 101 | 0.42 | 0.78 | 19 | empty |
| 5 | 73 | 0.40 | 0.79 | 13 | empty |
Compared structures
- 7V62 · Crystal structure of human osbp ord in complex with cholesterol · an experimental structure of the same protein · chain A against A, TM-score 0.48
- 7V62 · Crystal structure of human OSBP ORD in complex with cholesterol · an experimental structure of the same protein · chain A against A, TM-score 0.48
- 2RR3 · Solution structure of the complex between human vap-a msp domain and human osbp ffat motif · an experimental structure of the same protein · chain A against B, TM-score 0.04
- 2RR3 · Solution structure of the complex between human VAP-A MSP domain and human OSBP FFAT motif · an experimental structure of the same protein · chain A against B, TM-score 0.04
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22059
- Elsewhere: UniProt P22059 · AlphaFold DB P22059
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