MolNFT v1 · #282527 · protein
AlphaFold monomer V2.0 prediction for origin recognition complex subunit 2 (P32833)
P32833: “AlphaFold monomer V2.0 prediction for origin recognition complex subunit 2 (P32833)”. 6 pockets (best druggability 0.56). MolNFT v1 #282527 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P32833
- Type
- protein
- Length
- 620 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x429aA010A80A47FF4a2777bB34A2bba144d19df2
- Molecule
- Origin recognition complex subunit 2
- UniProt
- P32833
- Pockets
- 6 · best druggability 0.56
Structure
1 distinct chain · 35% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Origin recognition complex subunit 2 | protein | 620 | 35% helix, 6% strand | P32833 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 155 | 0.56 | 0.81 | 22 | empty |
| 2 | 189 | 0.48 | 0.76 | 25 | empty |
| 3 | 104 | 0.38 | 0.76 | 16 | empty |
| 4 | 87 | 0.38 | 0.76 | 15 | empty |
| 5 | 106 | 0.36 | 0.74 | 16 | empty |
Compared structures
- 6WGG · Atomic model of pre-insertion mutant OCCM-DNA complex(ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD… · an experimental structure of the same protein · chain A against B, TM-score 0.45
- 6WGG · Atomic model of pre-insertion mutant occm-DNA COMPLEX(ORC-CDC6-CDT1- MCM2-7 with MCM6 whd… · an experimental structure of the same protein · chain A against B, TM-score 0.45
- 6WGC · Atomic model of semi-attached mutant occm-DNA complex (orc-CDC6-CDT1- MCM2-7 with MCM6… · an experimental structure of the same protein · chain A against B, TM-score 0.45
- 6WGC · Atomic model of semi-attached mutant OCCM-DNA complex (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD… · an experimental structure of the same protein · chain A against B, TM-score 0.45
- 6WGI · Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on… · an experimental structure of the same protein · chain A against B, TM-score 0.45
- 6WGI · Atomic model of the mutant occm (orc-CDC6-CDT1-MCM2-7 with MCM6 whd truncation) loaded on… · an experimental structure of the same protein · chain A against B, TM-score 0.45
- 9BCX · Cryo-EM structure of the S. cerevisiae ORC-Cdc6-Mcm2-7-DNA complex with a fully closed… · an experimental structure of the same protein · chain A against C, TM-score 0.45
- 5V8F · Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1 · an experimental structure of the same protein · chain A against B, TM-score 0.44
- 5V8F · Structural basis of MCM2-7 replicative helicase loading by orc-CDC6 and CDT1 · an experimental structure of the same protein · chain A against B, TM-score 0.44
- 5ZR1 · Saccharomyces cerevisiae origin recognition complex bound to a 72-bp origin DNA… · an experimental structure of the same protein · chain A against B, TM-score 0.39
- 5ZR1 · Saccharomyces Cerevisiae Origin Recognition Complex Bound to a 72-bp Origin DNA… · an experimental structure of the same protein · chain A against B, TM-score 0.39
- 7TJF · S. cerevisiae ORC bound to 84 bp ARS1 DNA · an experimental structure of the same protein · chain A against B, TM-score 0.38
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P32833
- Elsewhere: UniProt P32833 · AlphaFold DB P32833
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