UniProt P32833
Origin recognition complex subunit 2 (P32833)
Origin recognition complex subunit 2 (UniProt P32833): 11 experimental structures and 1 predicted model on GenesisL1, 24 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P32833
- Protein
- Origin recognition complex subunit 2
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 24 · 6 records with a druggable one
Structures
12 records of P32833 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5V8F | Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1 | electron microscopy | B | — | 2 (best 0.87) |
| 5V8F | Structural basis of MCM2-7 replicative helicase loading by orc-CDC6 and CDT1 | electron microscopy | B | — | — |
| 5ZR1 | Saccharomyces cerevisiae origin recognition complex bound to a 72-bp origin DNA containing acs and… | electron microscopy | B | — | — |
| 6RQC | Cryo-EM structure of an MCM loading intermediate | electron microscopy | B | — | 2 (best 0.90) |
| 6WGC | Atomic model of semi-attached mutant occm-DNA complex (orc-CDC6-CDT1- MCM2-7 with MCM6 whd… | electron microscopy | B | — | — |
| 6WGG | Atomic model of pre-insertion mutant OCCM-DNA complex(ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) | electron microscopy | B | — | 4 (best 0.87) |
| 6WGG | Atomic model of pre-insertion mutant occm-DNA COMPLEX(ORC-CDC6-CDT1- MCM2-7 with MCM6 whd… | electron microscopy | B | — | — |
| 6WGI | Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at… | electron microscopy | B | — | 3 (best 0.86) |
| 6WGI | Atomic model of the mutant occm (orc-CDC6-CDT1-MCM2-7 with MCM6 whd truncation) loaded on DNA at… | electron microscopy | B | — | — |
| 7MCA | Structure of the S. cerevisiae origin recognition complex bound to the replication initiator Cdc6… | electron microscopy | B | — | 7 (best 0.88) |
| 7MCA | Structure of the S. cerevisiae origin recognition complex bound to the replication initiator CDC6… | electron microscopy | B | — | — |
| P32833 | AlphaFold monomer V2.0 prediction for origin recognition complex subunit 2 (P32833) | predicted | A | — | 6 (best 0.56) |
Experiment against prediction
- 7MCA chain B against the predicted model P32833: TM-score 0.90, RMSD 2.45 Å
- 7MCA chain B against the predicted model P32833: TM-score 0.90, RMSD 2.45 Å
- 6RQC chain B against the predicted model P32833: TM-score 0.90, RMSD 2.35 Å
- 6WGI chain B against the predicted model P32833: TM-score 0.81, RMSD 3.70 Å
- 6WGI chain B against the predicted model P32833: TM-score 0.81, RMSD 3.70 Å
- 6WGG chain B against the predicted model P32833: TM-score 0.81, RMSD 3.70 Å
- 6WGG chain B against the predicted model P32833: TM-score 0.81, RMSD 3.70 Å
- 6WGC chain B against the predicted model P32833: TM-score 0.81, RMSD 3.70 Å
- 5V8F chain B against the predicted model P32833: TM-score 0.78, RMSD 4.11 Å
- 5V8F chain B against the predicted model P32833: TM-score 0.78, RMSD 4.11 Å
Elsewhere
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