MolNFT v1 · #281953 · protein
AlphaFold monomer V2.0 prediction for rhodopsin (P02699)
P02699: “AlphaFold monomer V2.0 prediction for rhodopsin (P02699)”. 4 pockets (best druggability 0.83). MolNFT v1 #281953 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P02699
- Type
- protein
- Length
- 348 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7FDF8b382C6a36A8772D1A265E8e480c7DF0A9C1
- Molecule
- Rhodopsin
- UniProt
- P02699
- Pockets
- 4 · best druggability 0.83
Structure
1 distinct chain · 68% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Rhodopsin | protein | 348 | 68% helix, 4% strand | P02699 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 241 | 0.83 | 0.95 | 35 | empty |
| 2 | 276 | 0.62 | 0.80 | 24 | empty |
| 3 | 120 | 0.52 | 0.81 | 20 | empty |
| 4 | 58 | 0.31 | 0.75 | 10 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 5EN0 · Crystal Structure of T94I rhodopsin mutant · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 5EN0 · Crystal structure of T94I rhodopsin mutant · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 4X1H · Opsin/G(alpha) peptide complex stabilized by nonyl-glucoside · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 4X1H · OPSIN/G(ALPHA) peptide complex stabilized by nonyl-glucoside · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 6NWE · Crystal structure of bovine opsin with beta octyl glucoside bound · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 4BEY · Night blindness causing G90D rhodopsin in complex with GACT2 peptide · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 4BEY · Night blindness causing G90D rhodopsin in complex with GaCT2 peptide · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 4A4M · Crystal structure of the light-activated constitutively active N2C, M257Y,D282C rhodopsin… · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 4A4M · Crystal structure of the light-activated constitutively active N2C, M257Y,D282C rhodopsin… · an experimental structure of the same protein · chain A against A, TM-score 0.93
- 4BEZ · Night blindness causing G90D rhodopsin in the active conformation · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 4BEZ · Night blindness causing G90D rhodopsin in the active conformation · an experimental structure of the same protein · chain A against A, TM-score 0.92
- 4J4Q · Crystal structure of active conformation of GPCR opsin stabilized by octylglucoside · an experimental structure of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02699
- Elsewhere: UniProt P02699 · AlphaFold DB P02699
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