MolNFT v1 · #281417 · protein
AlphaFold monomer V2.0 prediction for dynamin-like 120 kda protein, mitochondrial (O60313)
O60313: “AlphaFold monomer V2.0 prediction for dynamin-like 120 kda protein, mitochondrial (O60313)”. 8 pockets (best druggability 0.63). MolNFT v1 #281417 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O60313
- Type
- protein
- Length
- 960 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5A5f617b5f7A19DF653B3530c1C72bf12240602A
- Molecule
- Dynamin-like 120 kda protein, mitochondrial
- UniProt
- O60313
- Pockets
- 8 · best druggability 0.63
Structure
1 distinct chain · 55% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dynamin-like 120 kda protein, mitochondrial | protein | 960 | 55% helix, 6% strand | O60313 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 298 | 0.63 | 0.80 | 41 | empty |
| 2 | 260 | 0.58 | 0.78 | 23 | empty |
| 3 | 175 | 0.54 | 0.79 | 30 | empty |
| 4 | 151 | 0.46 | 0.76 | 16 | empty |
| 5 | 87 | 0.45 | 0.80 | 17 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 8CT1 · CryoEM structure of human S-OPA1 assembled on lipid membrane in membrane-adjacent state · an experimental structure of the same protein · chain A against K, TM-score 0.71
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60313
- Elsewhere: UniProt O60313 · AlphaFold DB O60313
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