GL1X · GenesisL1 explorer

MolNFT v1 · #278265 · protein

AlphaFold monomer V2.0 prediction for nuclear RNA export factor 2 (Q9VV73)

Q9VV73: “AlphaFold monomer V2.0 prediction for nuclear RNA export factor 2 (Q9VV73)”. 9 pockets (best druggability 0.61). MolNFT v1 #278265 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q9VV73
Type
protein
Length
841 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x0056155E6B76709C124E31067C4d1B97cA9dA71a
Molecule
Nuclear RNA export factor 2
UniProt
Q9VV73
Pockets
9 · best druggability 0.61

Structure

1 distinct chain · 34% helix, 23% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANuclear RNA export factor 2protein84134% helix, 23% strandQ9VV73

Pockets

9 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14230.610.7631empty
22370.490.7423empty
3850.450.8022empty
41230.450.7727empty
51420.420.7524empty

Compared structures

  • 6MRK · Crystal structure of dmNxf2 NTF2-like domain in complex with Nxt1/p15 · an experimental structure of the same protein · chain A against B, TM-score 0.22
  • 6MRK · Crystal structure of DMNXF2 NTF2-like domain in complex with NXT1/P15 · an experimental structure of the same protein · chain A against B, TM-score 0.22
  • 6OPF · Crystal structure of dmNxf2 UBA domain fused with Panoramix helix · an experimental structure of the same protein · chain A against F, TM-score 0.07
  • 6OPF · Crystal structure of DMNXF2 uba domain fused with panoramix helix · an experimental structure of the same protein · chain A against F, TM-score 0.07

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