GL1X · GenesisL1 explorer

MolNFT v1 · #278156 · protein

AlphaFold monomer V2.0 prediction for transcription TERMINATION/ANTITERMINATION protein nusg (P0AFG1)

P0AFG1: “AlphaFold monomer V2.0 prediction for transcription TERMINATION/ANTITERMINATION protein nusg (P0AFG1)”. 1 pocket (best druggability 0.28). MolNFT v1 #278156 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P0AFG1
Type
protein
Length
181 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xf498a07CB267aF7A6C8376eAc13c07Cb31bc9C20
Molecule
Transcription TERMINATION/ANTITERMINATION protein nusg
UniProt
P0AFG1
Pockets
1 · best druggability 0.28

Structure

1 distinct chain · 22% helix, 33% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ATranscription TERMINATION/ANTITERMINATION protein nusgprotein18122% helix, 33% strandP0AFG1

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1590.280.7312empty

Compared structures

  • 6ZTJ · E. coli 70S-RNAP expressome complex in NusG-coupled state (38 nt intervening mRNA) · an experimental structure of the same protein · chain A against CF, TM-score 0.52
  • 6GOV · Structure of THE RNA POLYMERASE LAMBDA-BASED ANTITERMINATION COMPLEX · an experimental structure of the same protein · chain A against G, TM-score 0.51
  • 6GOV · Structure of the RNA polymerase lambda-based antitermination complex · an experimental structure of the same protein · chain A against G, TM-score 0.51
  • 6C6U · Cryoem structure of E.COLI RNA polymerase elongation complex bound with nusg · an experimental structure of the same protein · chain A against N, TM-score 0.48
  • 6C6U · CryoEM structure of E.coli RNA polymerase elongation complex bound with NusG · an experimental structure of the same protein · chain A against N, TM-score 0.48
  • 5TBZ · E. COLI RNA polymerase complexed with nusg · an experimental structure of the same protein · chain A against J, TM-score 0.38

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