UniProt P0AFG1

Transcription termination/antitermination protein NusG (P0AFG1)

Transcription termination/antitermination protein NusG (UniProt P0AFG1): 6 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: P0AFG1
Protein: Transcription termination/antitermination protein NusG
Experimental structures: 6
Predicted models: 1
Pockets: 6 · 2 records with a druggable one

Structures

7 records of P0AFG1 in the MolNFT archive: 6 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
5TBZ	E. COLI RNA polymerase complexed with nusg	x-ray diffraction	J, K	—	—
6C6U	CryoEM structure of E.coli RNA polymerase elongation complex bound with NusG	electron microscopy	N	—	2 (best 0.64)
6C6U	Cryoem structure of E.COLI RNA polymerase elongation complex bound with nusg	electron microscopy	N	—	—
6GOV	Structure of THE RNA POLYMERASE LAMBDA-BASED ANTITERMINATION COMPLEX	electron microscopy	G	—	3 (best 0.83)
6GOV	Structure of the RNA polymerase lambda-based antitermination complex	electron microscopy	G	—	—
6ZTJ	E. coli 70S-RNAP expressome complex in NusG-coupled state (38 nt intervening mRNA)	electron microscopy	CF	—	—
P0AFG1	AlphaFold monomer V2.0 prediction for transcription TERMINATION/ANTITERMINATION protein nusg…	predicted	A	—	1 (best 0.28)

Experiment against prediction

6C6U chain N against the predicted model P0AFG1: TM-score 0.84, RMSD 2.01 Å
6C6U chain N against the predicted model P0AFG1: TM-score 0.84, RMSD 2.01 Å
6ZTJ chain CF against the predicted model P0AFG1: TM-score 0.57, RMSD 2.97 Å
6GOV chain G against the predicted model P0AFG1: TM-score 0.53, RMSD 2.44 Å
6GOV chain G against the predicted model P0AFG1: TM-score 0.53, RMSD 2.44 Å
5TBZ chain J against the predicted model P0AFG1: TM-score 0.45, RMSD 2.10 Å

Elsewhere

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