MolNFT v1 · #273508 · protein
AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 5 (P03920)
P03920: “AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 5 (P03920)”. 6 pockets (best druggability 0.57). MolNFT v1 #273508 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P03920
- Type
- protein
- Length
- 606 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6DAA77C4263E74E745cA9c4D8E291e57e8991Cf5
- Molecule
- NADH-ubiquinone oxidoreductase chain 5
- UniProt
- P03920
- Pockets
- 6 · best druggability 0.57
Structure
1 distinct chain · 74% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH-ubiquinone oxidoreductase chain 5 | protein | 606 | 74% helix, 4% strand | P03920 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 164 | 0.57 | 0.81 | 20 | empty |
| 2 | 176 | 0.53 | 0.79 | 25 | empty |
| 3 | 133 | 0.45 | 0.76 | 19 | empty |
| 4 | 127 | 0.45 | 0.76 | 20 | empty |
| 5 | 111 | 0.37 | 0.74 | 18 | empty |
Compared structures
- 7QSN · Bovine complex I in lipid nanodisc, Deactive-apo · an experimental structure of the same protein · chain A against L, TM-score 0.99
- 7QSN · Bovine complex I in lipid nanodisc, deactive-apo · an experimental structure of the same protein · chain A against L, TM-score 0.99
- 8Q4A · Outward-facing, open1 proteoliposome complex I at 2.6 A. Initially purified in LMNG. · an experimental structure of the same protein · chain A against L, TM-score 0.99
- 7QSK · Bovine complex I in lipid nanodisc, Active-Q10 · an experimental structure of the same protein · chain A against L, TM-score 0.99
- 7QSK · Bovine complex I in lipid nanodisc, active-Q10 · an experimental structure of the same protein · chain A against L, TM-score 0.99
- 7QSM · Bovine complex I in lipid nanodisc, Deactive-ligand (composite) · an experimental structure of the same protein · chain A against L, TM-score 0.99
- 7QSM · Bovine complex I in lipid nanodisc, deactive-ligand (composite) · an experimental structure of the same protein · chain A against L, TM-score 0.99
- 7QSL · Bovine complex I in lipid nanodisc, Active-apo · an experimental structure of the same protein · chain A against L, TM-score 0.99
- 7QSL · Bovine complex I in lipid nanodisc, active-apo · an experimental structure of the same protein · chain A against L, TM-score 0.99
- 8Q49 · Outward-facing, open2 proteoliposome complex I at 2.6 A. Initially purified in LMNG. · an experimental structure of the same protein · chain A against L, TM-score 0.99
- 8Q48 · Outward-facing, closed proteoliposome complex I at 2.5 A. Initially purified in LMNG. · an experimental structure of the same protein · chain A against L, TM-score 0.99
- 7R41 · Bovine complex I in the presence of IM1761092, active class i (Composite map) · an experimental structure of the same protein · chain A against L, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03920
- Elsewhere: UniProt P03920 · AlphaFold DB P03920
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.