GL1X · GenesisL1 explorer

MolNFT v1 · #271667 · protein

AlphaFold monomer V2.0 prediction for nuclear pore complex protein NUP155 (O75694)

O75694: “AlphaFold monomer V2.0 prediction for nuclear pore complex protein NUP155 (O75694)”. 16 pockets (best druggability 0.78). MolNFT v1 #271667 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
O75694
Type
protein
Length
1,391 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x758850a3D7646b829972912E8A512268C74ceb66
Molecule
Nuclear pore complex protein NUP155
UniProt
O75694
Pockets
16 · best druggability 0.78

Structure

1 distinct chain · 45% helix, 14% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANuclear pore complex protein NUP155protein139145% helix, 14% strandO75694

Pockets

16 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
111850.780.7959empty
21400.770.9424empty
32560.750.8841empty
47940.720.7767empty
51900.510.7723empty

Compared structures

  • 5A9Q · Human nuclear pore complex · an experimental structure of the same protein · chain A against A, TM-score 0.60
  • 5A9Q · Human nuclear pore complex · an experimental structure of the same protein · chain A against A, TM-score 0.60
  • 5IJN · Composite structure of the inner ring of the human nuclear pore complex (32 copies of… · an experimental structure of the same protein · chain A against E, TM-score 0.58
  • 5IJO · Alternative composite structure of the inner ring of the human nuclear pore complex (16… · an experimental structure of the same protein · chain A against E, TM-score 0.58
  • 5IJO · Alternative composite structure of the inner ring of the human nuclear pore complex (16… · an experimental structure of the same protein · chain A against E, TM-score 0.58
  • 5IJN · Composite structure of the inner ring of the human nuclear pore complex (32 copies of… · an experimental structure of the same protein · chain A against E, TM-score 0.58
  • 7R1Y · Cryoem structure of human NUP155 (residues 19-981) · an experimental structure of the same protein · chain A against A, TM-score 0.50
  • 7EYQ · Cryo-EM (spa) structure of human NUP155 longer N-terminus (19-1069) at 5.4 ångström… · an experimental structure of the same protein · chain A against A, TM-score 0.49
  • 7PER · Model of the inner ring of the human nuclear pore complex · an experimental structure of the same protein · chain A against W, TM-score 0.45
  • 7EYE · Cryo-EM (spa) structure of NUP155 N-terminus (19-863) at 5.1 ångström resolution · an experimental structure of the same protein · chain A against A, TM-score 0.44

Analyse

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