MolNFT v1 · #270745 · protein
AlphaFold monomer V2.0 prediction for 5'(3')-deoxyribonucleotidase, cytosolic type (Q8TCD5)
Q8TCD5: “AlphaFold monomer V2.0 prediction for 5'(3')-deoxyribonucleotidase, cytosolic type (Q8TCD5)”. 3 pockets (best druggability 0.69). MolNFT v1 #270745 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8TCD5
- Type
- protein
- Length
- 201 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6DAA77C4263E74E745cA9c4D8E291e57e8991Cf5
- Molecule
- 5'(3')-deoxyribonucleotidase, cytosolic type
- UniProt
- Q8TCD5
- Pockets
- 3 · best druggability 0.69
Structure
1 distinct chain · 35% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 5'(3')-deoxyribonucleotidase, cytosolic type | protein | 201 | 35% helix, 14% strand | Q8TCD5 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 251 | 0.69 | 0.85 | 33 | empty |
| 2 | 71 | 0.32 | 0.75 | 18 | empty |
| 3 | 60 | 0.31 | 0.76 | 14 | empty |
Compared structures
- 2I7D · Structure of Human cytosolic deoxyribonucleotidase in complex with deoxyuridine, AlF4 and… · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 2I7D · Structure of human cytosolic deoxyribonucleotidase in complex with deoxyuridine, ALF4 and… · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 4YIH · Crystal structure of human cytosolic 5'(3')-deoxyribonucleotidase in complex with the… · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 4YIH · Crystal structure of human cytosolic 5'(3')-deoxyribonucleotidase in complex with the… · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 4L57 · High resolutin structure of human cytosolic 5'(3')- deoxyribonucleotidase · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 4L57 · High resolutin structure of human cytosolic 5'(3')-deoxyribonucleotidase · an experimental structure of the same protein · chain A against A, TM-score 0.95
- 6G2N · Crystal structure of human cytosolic 5'(3')-deoxyribonucleotidase in complex with the… · an experimental structure of the same protein · chain A against B, TM-score 0.95
- 6G2N · Crystal structure of human cytosolic 5'(3')-deoxyribonucleotidase in complex with the… · an experimental structure of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8TCD5
- Elsewhere: UniProt Q8TCD5 · AlphaFold DB Q8TCD5
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