MolNFT v1 · #270509 · protein

AlphaFold monomer V2.0 prediction for non-structural maintenance of chromosome element 4 (P43124)

P43124: “AlphaFold monomer V2.0 prediction for non-structural maintenance of chromosome element 4 (P43124)”. 5 pockets (best druggability 0.50). MolNFT v1 #270509 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: P43124
Type: protein
Length: 402 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x380F4C021CE17d70f3CC9D2B58C6c7D60cC516CA
Molecule: Non-structural maintenance of chromosome element 4
UniProt: P43124
Pockets: 5 · best druggability 0.50

Structure

1 distinct chain · 50% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Non-structural maintenance of chromosome element 4	protein	402	50% helix, 3% strand	P43124

Pockets

5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	152	0.50	0.78	21	empty
2	67	0.43	0.81	11	empty
3	87	0.40	0.77	17	empty
4	69	0.32	0.75	15	empty
5	62	0.27	0.72	13	empty

Compared structures

7TVE · ATP and DNA bound SMC5/6 core complex · an experimental structure of the same protein · chain A against G, TM-score 0.27
7YMD · Cryo-EM structure of Nse1/3/4 · an experimental structure of the same protein · chain A against A, TM-score 0.09

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P43124
Elsewhere: UniProt P43124 · AlphaFold DB P43124

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