MolNFT v1 · #270254 · protein
AlphaFold monomer V2.0 prediction for neuropilin-1 (Q9QWJ9)
Q9QWJ9: “AlphaFold monomer V2.0 prediction for neuropilin-1 (Q9QWJ9)”. 12 pockets (best druggability 0.68). MolNFT v1 #270254 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9QWJ9
- Type
- protein
- Length
- 922 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5efCceC43F089d52dB48a6C844E632024C0fA393
- Molecule
- Neuropilin-1
- UniProt
- Q9QWJ9
- Pockets
- 12 · best druggability 0.68
Structure
1 distinct chain · 8% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neuropilin-1 | protein | 922 | 8% helix, 36% strand | Q9QWJ9 |
Pockets
12 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1017 | 0.68 | 0.73 | 83 | empty |
| 2 | 319 | 0.63 | 0.79 | 41 | empty |
| 3 | 74 | 0.45 | 0.82 | 21 | empty |
| 4 | 218 | 0.45 | 0.73 | 25 | empty |
| 5 | 99 | 0.43 | 0.78 | 15 | empty |
Modifications
Observed in the structure: 8 disulfide (disulfide).
Compared structures
- 2ORX · Structural basis for ligand binding and heparin mediated activation of neuropilin · an experimental structure of the same protein · chain A against A, TM-score 0.34
- 2ORX · Structural Basis for Ligand Binding and Heparin Mediated Activation of Neuropilin · an experimental structure of the same protein · chain A against A, TM-score 0.34
- 2ORZ · Structural basis for ligand binding and heparin mediated activation of neuropilin · an experimental structure of the same protein · chain A against A, TM-score 0.33
- 2ORZ · Structural Basis for Ligand Binding and Heparin Mediated Activation of Neuropilin · an experimental structure of the same protein · chain A against A, TM-score 0.33
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9QWJ9
- Elsewhere: UniProt Q9QWJ9 · AlphaFold DB Q9QWJ9
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