MolNFT v1 · #269099 · protein

AlphaFold monomer V2.0 prediction for nuclear receptor subfamily 6 group a member 1 (Q64249)

Q64249: “AlphaFold monomer V2.0 prediction for nuclear receptor subfamily 6 group a member 1 (Q64249)”. 8 pockets (best druggability 0.73). MolNFT v1 #269099 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q64249
Type: protein
Length: 495 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x025f3b1a898b05AD2731bE6Ab72687b5920c4A3F
Molecule: Nuclear receptor subfamily 6 group a member 1
UniProt: Q64249
Pockets: 8 · best druggability 0.73

Structure

1 distinct chain · 43% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nuclear receptor subfamily 6 group a member 1	protein	495	43% helix, 2% strand	Q64249

Pockets

8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	247	0.73	0.87	27	empty
2	377	0.63	0.78	38	empty
3	134	0.44	0.76	21	empty
4	99	0.38	0.75	12	empty
5	92	0.38	0.76	22	empty

Compared structures

5KRB · GCNF DNA Binding Domain - Oct4 DR0 Complex · an experimental structure of the same protein · chain A against G, TM-score 0.16
5KRB · Gcnf DNA binding domain - OCT4 DR0 complex · an experimental structure of the same protein · chain A against G, TM-score 0.16

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q64249
Elsewhere: UniProt Q64249 · AlphaFold DB Q64249

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