MolNFT v1 · #269005 · protein
AlphaFold monomer V2.0 prediction for nuclear receptor subfamily 0 group B member 2 (Q15466)
Q15466: “AlphaFold monomer V2.0 prediction for nuclear receptor subfamily 0 group B member 2 (Q15466)”. 3 pockets (best druggability 0.42). MolNFT v1 #269005 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q15466
- Type
- protein
- Length
- 257 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5e58272ea25a05e06901A2eAe9f63939b344e0c6
- Molecule
- Nuclear receptor subfamily 0 group B member 2
- UniProt
- Q15466
- Pockets
- 3 · best druggability 0.42
Structure
1 distinct chain · 59% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nuclear receptor subfamily 0 group B member 2 | protein | 257 | 59% helix, 3% strand | Q15466 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 155 | 0.42 | 0.74 | 24 | empty |
| 2 | 75 | 0.35 | 0.76 | 13 | empty |
| 3 | 56 | 0.33 | 0.77 | 17 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 4ONI · Structure of Human Orphan Receptor LRH1 bound to two bacterial phospholipids · an experimental structure of the same protein · chain A against C, TM-score 0.05
- 4ONI · Structure of human orphan receptor LRH1 bound to two bacterial phospholipids · an experimental structure of the same protein · chain A against C, TM-score 0.05
- 1YUC · Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, Bound to Phospholipid and a… · an experimental structure of the same protein · chain A against C, TM-score 0.05
- 1YUC · Human nuclear receptor liver receptor homologue-1, lrh-1, bound to phospholipid and a… · an experimental structure of the same protein · chain A against C, TM-score 0.05
- 7YXD · Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment · an experimental structure of the same protein · chain A against J, TM-score 0.05
- 4DOR · Human nuclear receptor liver receptor homologue-1, lrh-1, in its apo state bound to a… · an experimental structure of the same protein · chain A against C, TM-score 0.04
- 4DOR · Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, in its apo State Bound to a… · an experimental structure of the same protein · chain A against C, TM-score 0.04
- 7YXC · Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment · an experimental structure of the same protein · chain A against R, TM-score 0.04
- 6W9M · Structure of the ancestral glucocorticoid receptor 2 ligand binding domain in complex… · an experimental structure of the same protein · chain A against B, TM-score 0.04
- 7YXN · Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment · an experimental structure of the same protein · chain A against R, TM-score 0.04
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15466
- Elsewhere: UniProt Q15466 · AlphaFold DB Q15466
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