UniProt Q15466
SHP NR Box 1 Peptide (Q15466)
SHP NR Box 1 Peptide (UniProt Q15466): 14 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15466
- Protein
- SHP NR Box 1 Peptide
- Experimental structures
- 14
- Predicted models
- 1
- Pockets
- 4 · 0 records with a druggable one
Structures
15 records of Q15466 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1YUC | Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, Bound to Phospholipid and a Fragment of… | x-ray diffraction | C, D | — | — |
| 1YUC | Human nuclear receptor liver receptor homologue-1, lrh-1, bound to phospholipid and a fragment of… | x-ray diffraction | C, D | — | — |
| 2Q3Y | Ancestral Corticiod Receptor in Complex with DOC | x-ray diffraction | B | — | — |
| 2Q3Y | Ancestral corticiod receptor in complex with doc | x-ray diffraction | B | — | — |
| 2Z4J | Crystal structure of AR LBD with SHP peptide NR Box 2 | x-ray diffraction | B | — | — |
| 2Z4J | Crystal structure of ar lbd with shp peptide nr box 2 | x-ray diffraction | B | — | — |
| 4DOR | Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, in its apo State Bound to a Fragment of… | x-ray diffraction | C, D | — | — |
| 4DOR | Human nuclear receptor liver receptor homologue-1, lrh-1, in its apo state bound to a fragment of… | x-ray diffraction | C, D | — | — |
| 4ONI | Structure of Human Orphan Receptor LRH1 bound to two bacterial phospholipids | x-ray diffraction | C, D | — | — |
| 4ONI | Structure of human orphan receptor LRH1 bound to two bacterial phospholipids | x-ray diffraction | C, D | — | — |
| 6W9M | Structure of the ancestral glucocorticoid receptor 2 ligand binding domain in complex with… | x-ray diffraction | B | — | — |
| 7YXC | Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment | x-ray diffraction | R | — | — |
| 7YXD | Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment | x-ray diffraction | C, F, J, N | — | 1 (best 0.31) |
| 7YXN | Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment | x-ray diffraction | R, S | — | — |
| Q15466 | AlphaFold monomer V2.0 prediction for nuclear receptor subfamily 0 group B member 2 (Q15466) | predicted | A | — | 3 (best 0.42) |
Experiment against prediction
- 4DOR chain D against the predicted model Q15466: TM-score 0.79, RMSD 0.31 Å
- 4DOR chain D against the predicted model Q15466: TM-score 0.79, RMSD 0.31 Å
- 2Q3Y chain B against the predicted model Q15466: TM-score 0.78, RMSD 0.33 Å
- 2Q3Y chain B against the predicted model Q15466: TM-score 0.78, RMSD 0.33 Å
- 7YXN chain R against the predicted model Q15466: TM-score 0.76, RMSD 1.44 Å
- 4ONI chain D against the predicted model Q15466: TM-score 0.75, RMSD 0.35 Å
- 4ONI chain D against the predicted model Q15466: TM-score 0.75, RMSD 0.35 Å
- 7YXC chain R against the predicted model Q15466: TM-score 0.74, RMSD 1.21 Å
- 6W9M chain B against the predicted model Q15466: TM-score 0.74, RMSD 1.22 Å
- 2Z4J chain B against the predicted model Q15466: TM-score 0.73, RMSD 0.58 Å
Elsewhere
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