GL1X · GenesisL1 explorer

MolNFT v1 · #267053 · protein

AlphaFold monomer V2.0 prediction for ribosome biogenesis protein ENP2 (P48234)

P48234: “AlphaFold monomer V2.0 prediction for ribosome biogenesis protein ENP2 (P48234)”. 3 pockets (best druggability 0.80). MolNFT v1 #267053 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P48234
Type
protein
Length
707 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x661E995327D4c9b99E17Cca11ea8072ed8a218Dd
Molecule
Ribosome biogenesis protein ENP2
UniProt
P48234
Pockets
3 · best druggability 0.80

Structure

1 distinct chain · 23% helix, 28% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARibosome biogenesis protein ENP2protein70723% helix, 28% strandP48234

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18700.800.8358empty
24900.660.7740empty
3650.310.7415empty

Compared structures

  • 5WLC · The complete structure of the small subunit processome · an experimental structure of the same protein · chain A against LV, TM-score 0.49
  • 6LQP · Cryo-EM structure of 90S small subunit preribosomes in transition states (State A) · an experimental structure of the same protein · chain A against RA, TM-score 0.47
  • 6LQQ · Cryo-EM structure of 90S small subunit preribosomes in transition states (State B) · an experimental structure of the same protein · chain A against RA, TM-score 0.47
  • 6LQR · Cryo-EM structure of 90S small subunit preribosomes in transition states (State C) · an experimental structure of the same protein · chain A against RA, TM-score 0.47
  • 6LQU · Cryo-EM structure of 90S small subunit preribosomes in transition states (State A1) · an experimental structure of the same protein · chain A against RA, TM-score 0.47
  • 6LQV · Cryo-EM structure of 90S small subunit preribosomes in transition states (State C1) · an experimental structure of the same protein · chain A against RA, TM-score 0.47

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