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AlphaFold monomer V2.0 prediction for ribosome biogenesis protein ENP2 (P48234)

Analyse AlphaFold monomer V2.0 prediction for ribosome biogenesis protein ENP2 (P48234) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P48234
Type
protein
Length
707 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x661E995327D4c9b99E17Cca11ea8072ed8a218Dd
Molecule
Ribosome biogenesis protein ENP2
UniProt
P48234
Pockets
3 · best druggability 0.80

Structure

1 distinct chain · 23% helix, 28% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARibosome biogenesis protein ENP2protein70723% helix, 28% strandP48234

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
18700.800.8358empty
24900.660.7740empty
3650.310.7415empty

Compared structures

  • 7SUK · Structure of Bfr2-Lcp5 Complex Observed in the Small Subunit Processome Isolated from… · an experimental structure of the same protein · chain A against LV, TM-score 0.49
  • 5WLC · The complete structure of the small subunit processome · an experimental structure of the same protein · chain A against LV, TM-score 0.49
  • 6ZQB · Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state B2 · an experimental structure of the same protein · chain A against JC, TM-score 0.49
  • 7AJT · Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) · an experimental structure of the same protein · chain A against JC, TM-score 0.48
  • 6ZQC · Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Pre-A1 · an experimental structure of the same protein · chain A against JC, TM-score 0.48
  • 6LQV · Cryo-EM structure of 90S small subunit preribosomes in transition states (State C1) · an experimental structure of the same protein · chain A against RA, TM-score 0.47
  • 6LQP · Cryo-EM structure of 90S small subunit preribosomes in transition states (State A) · an experimental structure of the same protein · chain A against RA, TM-score 0.47
  • 6LQR · Cryo-EM structure of 90S small subunit preribosomes in transition states (State C) · an experimental structure of the same protein · chain A against RA, TM-score 0.47
  • 6LQQ · Cryo-EM structure of 90S small subunit preribosomes in transition states (State B) · an experimental structure of the same protein · chain A against RA, TM-score 0.47
  • 6LQU · Cryo-EM structure of 90S small subunit preribosomes in transition states (State A1) · an experimental structure of the same protein · chain A against RA, TM-score 0.47
  • 7D63 · Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) · an experimental structure of the same protein · chain A against RA, TM-score 0.47
  • 6KE6 · 3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome · an experimental structure of the same protein · chain A against RA, TM-score 0.47

Analyse

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