GL1X · GenesisL1 explorer

MolNFT v1 · #266727 · protein

AlphaFold monomer V2.0 prediction for nucleolar complex protein 2 (P39744)

P39744: “AlphaFold monomer V2.0 prediction for nucleolar complex protein 2 (P39744)”. 6 pockets (best druggability 0.69). MolNFT v1 #266727 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P39744
Type
protein
Length
710 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x7FDF8b382C6a36A8772D1A265E8e480c7DF0A9C1
Molecule
Nucleolar complex protein 2
UniProt
P39744
Pockets
6 · best druggability 0.69

Structure

1 distinct chain · 63% helix, 2% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANucleolar complex protein 2protein71063% helix, 2% strandP39744

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16220.690.7755empty
27520.670.7562empty
33660.600.7745empty
41780.450.7421empty
51450.410.7414empty

Compared structures

  • 7R72 · State E1 nucleolar 60S ribosome biogenesis intermediate - Spb4 local model · an experimental structure of the same protein · chain A against 8, TM-score 0.05
  • 7NAF · State E2 nucleolar 60S ribosomal biogenesis intermediate - Spb1-MTD local model · an experimental structure of the same protein · chain A against 8, TM-score 0.05

Analyse

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