MolNFT v1 · #266637 · protein
AlphaFold monomer V2.0 prediction for NAD(P) transhydrogenase, mitochondrial (Q13423)
Q13423: “AlphaFold monomer V2.0 prediction for NAD(P) transhydrogenase, mitochondrial (Q13423)”. 10 pockets (best druggability 0.79). MolNFT v1 #266637 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q13423
- Type
- protein
- Length
- 1,086 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xa89dD03CFEE746722fED0F92511388420DCdbbdB
- Molecule
- NAD(P) transhydrogenase, mitochondrial
- UniProt
- Q13423
- Pockets
- 10 · best druggability 0.79
Structure
1 distinct chain · 54% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NAD(P) transhydrogenase, mitochondrial | protein | 1086 | 54% helix, 10% strand | Q13423 |
Pockets
10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1164 | 0.79 | 0.80 | 95 | empty |
| 2 | 482 | 0.72 | 0.81 | 51 | empty |
| 3 | 255 | 0.54 | 0.76 | 30 | empty |
| 4 | 120 | 0.47 | 0.78 | 24 | empty |
| 5 | 118 | 0.45 | 0.77 | 17 | empty |
Compared structures
- 1PT9 · Crystal Structure Analysis of the DIII Component of Transhydrogenase with a… · an experimental structure of the same protein · chain A against A, TM-score 0.16
- 1PT9 · Crystal structure analysis of the diii component of transhydrogenase with a… · an experimental structure of the same protein · chain A against A, TM-score 0.16
- 1DJL · The crystal structure of human transhydrogenase domain III with bound NADP · an experimental structure of the same protein · chain A against A, TM-score 0.16
- 1DJL · The crystal structure of human transhydrogenase domain III with bound NADP · an experimental structure of the same protein · chain A against A, TM-score 0.16
- 1U31 · recombinant human heart transhydrogenase dIII bound with NADPH · an experimental structure of the same protein · chain A against A, TM-score 0.16
- 1U31 · Recombinant human heart transhydrogenase diii bound with NADPH · an experimental structure of the same protein · chain A against A, TM-score 0.16
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13423
- Elsewhere: UniProt Q13423 · AlphaFold DB Q13423
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.