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AlphaFold monomer V2.0 prediction for NAD(P) transhydrogenase, mitochondrial (Q13423)

Analyse AlphaFold monomer V2.0 prediction for NAD(P) transhydrogenase, mitochondrial… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q13423
Type
protein
Length
1,086 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xa89dD03CFEE746722fED0F92511388420DCdbbdB
Molecule
NAD(P) transhydrogenase, mitochondrial
UniProt
Q13423
Pockets
10 · best druggability 0.79

Structure

1 distinct chain · 54% helix, 10% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANAD(P) transhydrogenase, mitochondrialprotein108654% helix, 10% strandQ13423

Pockets

10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
111640.790.8095empty
24820.720.8151empty
32550.540.7630empty
41200.470.7824empty
51180.450.7717empty

Compared structures

  • 1PT9 · Crystal Structure Analysis of the DIII Component of Transhydrogenase with a… · an experimental structure of the same protein · chain A against A, TM-score 0.16
  • 1PT9 · Crystal structure analysis of the diii component of transhydrogenase with a… · an experimental structure of the same protein · chain A against A, TM-score 0.16
  • 1DJL · The crystal structure of human transhydrogenase domain III with bound NADP · an experimental structure of the same protein · chain A against A, TM-score 0.16
  • 1DJL · The crystal structure of human transhydrogenase domain III with bound NADP · an experimental structure of the same protein · chain A against A, TM-score 0.16
  • 1U31 · recombinant human heart transhydrogenase dIII bound with NADPH · an experimental structure of the same protein · chain A against A, TM-score 0.16
  • 1U31 · Recombinant human heart transhydrogenase diii bound with NADPH · an experimental structure of the same protein · chain A against A, TM-score 0.16

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