MolNFT v1 · #266050 · protein
AlphaFold monomer V2.0 prediction for nlr family card domain- containing protein 4 (Q9NPP4)
Q9NPP4 · Nlr family card domain-containing protein 4: “AlphaFold monomer V2.0 prediction for nlr family card domain- containing protein 4 (Q9NPP4)”. 10 pockets (best druggability 0.89). MolNFT v1 #266050 on GenesisL1: 3D structure, binding…
- Accession
- Q9NPP4
- Type
- protein
- Length
- 1,024 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xe79229995410d23f4cc5cf100E458Ad3DD58ed38
- Molecule
- Nlr family card domain-containing protein 4
- UniProt
- Q9NPP4
- Pockets
- 10 · best druggability 0.89
Structure
1 distinct chain · 48% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nlr family card domain-containing protein 4 | protein | 1024 | 48% helix, 12% strand | Q9NPP4 |
Pockets
10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 976 | 0.89 | 0.90 | 128 | empty |
| 2 | 758 | 0.83 | 0.86 | 69 | empty |
| 3 | 124 | 0.60 | 0.86 | 25 | empty |
| 4 | 62 | 0.45 | 0.83 | 14 | empty |
| 5 | 180 | 0.44 | 0.74 | 24 | empty |
Compared structures
- 8FVU · Cryo-EM structure of human Needle/NAIP/NLRC4 (R288A) · an experimental structure of the same protein · chain A against B, TM-score 0.65
- 8FW9 · Cryo-EM structure of full-length human NLRC4 inflammasome with C12 symmetry · an experimental structure of the same protein · chain A against A, TM-score 0.65
- 6MKS · Cryo-EM structure of NLRC4-CARD filament · an experimental structure of the same protein · chain A against A, TM-score 0.09
- 6MKS · Cryo-EM structure of NLRC4-card filament · an experimental structure of the same protein · chain A against A, TM-score 0.09
- 6N1I · Cryo-EM structure of NLRC4-card filament · an experimental structure of the same protein · chain A against A, TM-score 0.08
- 6K8J · Structure of NLRC4 card filament · an experimental structure of the same protein · chain A against G, TM-score 0.08
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NPP4
- Elsewhere: UniProt Q9NPP4 · AlphaFold DB Q9NPP4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.