MolNFT v1 · #265946 · protein

AlphaFold monomer V2.0 prediction for neuroligin-1 (Q8N2Q7)

Q8N2Q7: “AlphaFold monomer V2.0 prediction for neuroligin-1 (Q8N2Q7)”. 9 pockets (best druggability 0.70). MolNFT v1 #265946 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q8N2Q7
Type: protein
Length: 863 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xd10960F956646DE8b64d3598984c91C2d5Af3D7b
Molecule: Neuroligin-1
UniProt: Q8N2Q7
Pockets: 9 · best druggability 0.70

Structure

1 distinct chain · 32% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Neuroligin-1	protein	863	32% helix, 10% strand	Q8N2Q7

Pockets

9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	751	0.70	0.77	59	empty
2	88	0.70	0.93	18	empty
3	180	0.70	0.88	30	empty
4	388	0.68	0.81	50	empty
5	285	0.57	0.77	28	empty

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

5OJ6 · Crystal structure of the chicken MDGA1 ectodomain in complex with the human neuroligin 1… · an experimental structure of the same protein · chain A against A, TM-score 0.63
5OJ6 · Crystal structure of the chicken MDGA1 ectodomain in complex with the human neuroligin 1… · an experimental structure of the same protein · chain A against A, TM-score 0.63
5OJK · Crystal structure of the human neuroligin 1 cholinesterase domain containing spliced… · an experimental structure of the same protein · chain A against A, TM-score 0.62

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8N2Q7
Elsewhere: UniProt Q8N2Q7 · AlphaFold DB Q8N2Q7

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