Research workbench
AlphaFold monomer V2.0 prediction for neuroligin-1 (Q8N2Q7)
Analyse AlphaFold monomer V2.0 prediction for neuroligin-1 (Q8N2Q7) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q8N2Q7
- Type
- protein
- Length
- 863 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd10960F956646DE8b64d3598984c91C2d5Af3D7b
- Molecule
- Neuroligin-1
- UniProt
- Q8N2Q7
- Pockets
- 9 · best druggability 0.70
Structure
1 distinct chain · 32% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neuroligin-1 | protein | 863 | 32% helix, 10% strand | Q8N2Q7 |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 751 | 0.70 | 0.77 | 59 | empty |
| 2 | 88 | 0.70 | 0.93 | 18 | empty |
| 3 | 180 | 0.70 | 0.88 | 30 | empty |
| 4 | 388 | 0.68 | 0.81 | 50 | empty |
| 5 | 285 | 0.57 | 0.77 | 28 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 5OJ6 · Crystal structure of the chicken MDGA1 ectodomain in complex with the human neuroligin 1… · an experimental structure of the same protein · chain A against A, TM-score 0.63
- 5OJ6 · Crystal structure of the chicken MDGA1 ectodomain in complex with the human neuroligin 1… · an experimental structure of the same protein · chain A against A, TM-score 0.63
- 5OJK · Crystal structure of the human neuroligin 1 cholinesterase domain containing spliced… · an experimental structure of the same protein · chain A against A, TM-score 0.62
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8N2Q7
- Elsewhere: UniProt Q8N2Q7 · AlphaFold DB Q8N2Q7
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