MolNFT v1 · #265796 · protein
AlphaFold monomer V2.0 prediction for neuromedin-K receptor (P29371)
P29371: “AlphaFold monomer V2.0 prediction for neuromedin-K receptor (P29371)”. 3 pockets (best druggability 0.80). MolNFT v1 #265796 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P29371
- Type
- protein
- Length
- 465 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7FDF8b382C6a36A8772D1A265E8e480c7DF0A9C1
- Molecule
- Neuromedin-K receptor
- UniProt
- P29371
- Pockets
- 3 · best druggability 0.80
Structure
1 distinct chain · 54% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neuromedin-K receptor | protein | 465 | 54% helix, 3% strand | P29371 |
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 149 | 0.80 | 0.96 | 24 | empty |
| 2 | 499 | 0.70 | 0.80 | 51 | empty |
| 3 | 197 | 0.51 | 0.77 | 24 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 8JBF · Senktide bound to active human neurokinin 3 receptor in complex with Gq · an experimental structure of the same protein · chain A against B, TM-score 0.57
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P29371
- Elsewhere: UniProt P29371 · AlphaFold DB P29371
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