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AlphaFold monomer V2.0 prediction for neuromedin-K receptor (P29371)

Analyse AlphaFold monomer V2.0 prediction for neuromedin-K receptor (P29371) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: P29371
Type: protein
Length: 465 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7FDF8b382C6a36A8772D1A265E8e480c7DF0A9C1
Molecule: Neuromedin-K receptor
UniProt: P29371
Pockets: 3 · best druggability 0.80

Structure

1 distinct chain · 54% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Neuromedin-K receptor	protein	465	54% helix, 3% strand	P29371

Pockets

3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	149	0.80	0.96	24	empty
2	499	0.70	0.80	51	empty
3	197	0.51	0.77	24	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

8JBF · Senktide bound to active human neurokinin 3 receptor in complex with Gq · an experimental structure of the same protein · chain A against B, TM-score 0.57

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P29371
Elsewhere: UniProt P29371 · AlphaFold DB P29371

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